Vés al contingut (premeu Retorn)


Publicacions del Grup BBT en els darrers 5 anys


  1. J. Guillem-Marti, G. Boix-Lemonche, D. Gugutkov, M.P. Ginebra, G. Altankov, J.M. Manero. Recombinant fibronectin fragment III8-10/polylactic acid hybrid nanofibers enhance the bioactivity of titanium surface. Nanomedicine (Lond). 2018 Apr;13(8):899-912. Epub 2018 Mar 22. doi: 10.2217/nnm-2017-0342

  2. M. Hoyos-Nogués, J. Buxadera-Palomero, M.-P. Ginebra, J.M. Manero, F.X. Gil, C. Mas-Moruno. All-in-one trifunctional strategy: A cell adhesive, bacteriostatic and bactericidal coating for titanium implants. Colloids and Surfaces B: Biointerfaces 169 (2018) 30–40. doi: 10.1016/j.colsurfb.2018.04.050

  3. G. Scionti, L. Rodriguez-Arco, M.T. Lopez-Lopez, A.L. Medina-Castillo, I. Garzón, M. Alaminos, M. Toledano, R. Osorio. Effect of functionalized PHEMA micro- and nano-particles on the viscoelastic properties of fibrin-agarose biomaterials. J Biomed Mater Res A. 2018 Mar;106(3):738-745. doi: 10.1002/jbm.a.36275

  4. C. Lo Porto, F. Palumbo, J. Buxadera-Palomero, C, Canal, P. Jelinek, L. Zajickova, P. Favia. On the plasma deposition of vancomycin-containing nano-capsules for drug-delivery applications. Plasma Process Polym. 2018;e1700232. doi: doi.org/10.1002/ppap.201700232

  5. A. Brizuela-Velasco, E. Pérez-Pevida, A. Jiménez-Garrudo, F.J. Gil-Mur, J.M. Manero, M. Punset-Fuste, D. Chávarri-Prado, M. Diéguez-Pereira6, F. Monticelli. Mechanical Characterisation and Biomechanical and Biological Behaviours of Ti-Zr Binary-Alloy Dental Implants. BioMed Research International, Volume 2017, Article ID 2785863, 10 pages. doi: doi.org/10



  1. A. Barba, A. Diez-Escudero, Y. Maazouz, K. Rappe, M. Espanol, E.B. Montufar, M. Bonany, J.M. Sadowska, J: Guillem-Marti, C. Öhman-Mägi, C. Persson, M.C. Manzanares, J. Franch, M.P. Ginebra. Osteoinduction by Foamed and 3D-Printed Calcium Phosphate Scaffolds: Effect of Nanostructure and Pore Architecture. ACS Appl Mater Interfaces. 2017 Nov 20. doi: 10.1021/acsami.7b14175

  2. M. Hoyos-Nogués, F. Velasco, M.-P. Ginebra, J.M. Manero, F.X. Gil and C. Mas-Moruno. Regenerating bone via multifunctional coatings: the blending of cell integration and bacterial inhibition properties on the surface of biomaterials. ACS Appl Mater Interfaces. 2017 Jul 5;9(26):21618-21630. doi: 10.1021/acsami.7b03127.

  3. Y. Maazouz, E.B. Montufar, J. Malbert, M. Espanol, M.P.Ginebra. Self-hardening and thermoresponsive alpha tricalcium phosphate/pluronic pastes. Acta Biomaterialia 49 (2017) 563-574. doi: dx.doi.org/10.1016/j.actbio.2016.11.043.

  4. A. Diez-Escudero, M. Espanol, S. Beats, M.P. Ginebra. In vitro degradation of calcium phosphates: effect of multiscale porosity, textural properties and composition. Acta Biomaterialia 60 (2017):81-92. doi: doi.org/10.1016/j.actbio.2017.07.033.

  5. R. O'Neill, H.O. McCarthy, E. Montufar, M.P. Ginebra, D.I. Wilson, A. Lennon, N. Dunne. Critical Review: Injectability of Calcium Phosphate Pastes and Cements. Acta Biomaterialia 50, 1 March 2017, Pages 1–19. doi: dx.doi.org/10.1016/j.actbio.2016.11.019.

  6. G. Ciapetti, G. di Pompo, A. Diez-Escudero, E.B. Montufar, M.P. Ginebra S. Avnet, D. Martini, N. Baldini. Osteoclast differentiation from human blood precursors on biomimetic calcium-phosphate substrates. Acta Biomaterialia 50, 1 March 2017, Pages 102–113. doi: dx.doi.org/10.1016/j.actbio.2016.12.013.

  7. C. Canal, R. Fontelo, I. Hamouda, J. Guillem-Martí, U. Cvelbar, M.P. Ginebra. Plasma-induced selectivity in bone cancer cells death. Free Radical Biology and Medicine 110 (2017) 72-80. doi: doi.org/10.1016/j.freeradbiomed.2017.05.023.

  8. T.G. Kapp, F. Rechenmacher, S. Neubauer, O.V. Maltsev, E.A. Cavalcanti-Adam, R. Zarka, U. Reuning, J. Notni, H-J Wester, C. Mas-Moruno, J. Spatz, B. Geiger, H. Kessler. A Comprehensive Evaluation of the Activity and Selectivity Profile of Ligands for RGD-binding Integrins. Scientific Reports 7, Article number: 39805 (2017). doi:10.1038/srep39805

  9. R. Schieber, F. Lasserre, M. Hans, M. Fernández-Yagüe, M. Díaz-Ricart, G. Escolar, M.P. Ginebra, F. Mücklich, M. Pegueroles. Controlled endothelial cell and platelet adhesion onto patterned CoCr alloy surfaces by Direct Laser Interference Patterning technique for cardiovascular applications. Adv Healthc Mater. 2017 Jul 17. doi: 10.1002/adhm.201700327.

  10. A. Diez-Escudero, M. Espanol, X. Lu, C. Persson, M.-P. Ginebra. Heparinization of Beta Tricalcium Phosphate: Osteoimmunomodulatory Effects. Advanced Healthcare Materials, accepted November 2017.

  11. R. Fraioli, P.M. Tsimbouri, L.E. Fisher, A.H. Nobbs, B. Su, S. Neubauer, F. Rechenmacher, H. Kessler, M.P. Ginebra, M.J. Dalby, J.M. Manero, C Mas-Moruno. Towards the cell-instructive bactericidal substrate: exploring the combination of nanotopographical features and integrin selective synthetic ligands. Scientific Reports 7, Article number: 16363 (2017). doi:10.1038/s41598-017-16385-3.

  12. M. Motisuke, G. Mestres, C. O. Renó, R.G. Carrodeguas, C.A.C. Zavaglia, M.P. Ginebra. Influence of Si substitution on the reactivity of α-Tricalcium Phosphate. Materials Science and Engineering C, Volume 75, 1 June 2017, Pages 816-821. doi: doi.org/10.1016/j.msec.2017.02.099.

  13. J. Buxadera-Palomero, C. Calvo, S. Torrent-Camarero, F.J. Gil, C. Mas-Moruno, C. Canal, D. Rodríguez. Biofunctional polyethylene glycol coatings on titanium: An in vitro-based comparison of functionalization methods. Colloids Surf B Biointerfaces. 2017 Jan 24;152:367-375. doi: 10.1016/j.colsurfb.2017.01.042.

  14. A. Diez-Escudero, M. Espanol, E.B. Montufar, G. Di Pompo, G. Ciapetti, N. Baldini, M.P. Ginebra. Focus ion beam / Scanning electron microscopy characterisation of osteoclastic resorption of calcium phosphate substrates. Tissue Eng Part C Methods. 2017 Feb;23(2):118-124. doi: 10.1089/ten.TEC.2016.0361.

  15. J.M. Sadowska, J. Guillem-Marti, E.B. Montufar, M. Espanol, M.P. Ginebra. Biomimetic versus Sintered Calcium Phosphates: The in vitro Behavior of Osteoblasts and Mesenchymal Stem Cells. Tissue Eng Part A. 2017 Jan 20. doi: 10.1089/ten.TEA.2016.0406.

  16. A. Rodríguez-Contreras, Y. García, J.M. Manero, E. Rupérez. Antibacterial PHAs coating for titanium implants. European Polymer Journal. Volume 90, May 2017, Pages 66–78. doi: doi.org/10.1016/j.eurpolymj.2017.03.004.

  17. M.I. Castellanos, J. Guillem-Marti, C. Mas-Moruno, M. Díaz-Ricart, G. Escolar, M.P. Ginebra, F.J. Gil, M. Pegueroles, J.M. Manero. Cell adhesive peptides functionalized on CoCr alloy stimulate endothelialization and prevent thrombogenesis and restenosis. J Biomed Mater Res Part A 2017:00A:000–000. doi: 10.1002/jbm.a.35988.

  18. M.I. Castellanos, C. Mas-Moruno, A. Graua, X. Serra-Picamal, X. Trepat, F. Albericio, M. Joner, F.J. Gil, M.P. Ginebra, J.M. Manero, M. Pegueroles. Functionalization of CoCr surfaces with cell adhesive peptides to promote HUVECs adhesion and proliferation. Applied Surface Science 393 (2017) 82–92. doi: dx.doi.org/10.1016/j.apsusc.2016.09.107.

  19. I. Ajaxon, A. Acciaioli, G. Lionello, M.P. Ginebra, C. Öhman-Mägi, M. Baleani, C. Persson. Elastic properties and strain-to-crack-initiation of calcium phosphate bone cements: revelations of a high-resolution measurement technique. J Mech Behav Biomed Mater. 2017 Oct;74:428-437. doi: 10.1016/j.jmbbm.2017.06.023.

  20. S. Gallinetti, G. Mestres, C. Canal, C. Persson, M.P. Ginebra. A novel strategy to enhance interfacial adhesion in fiber-reinforced calcium phosphate cement. Journal of Mechanical Behaviour of Biomedical Materials 75 (2017) :495-503. doi: 10.1016/j.jmbbm.2017.08.017.

  21. U. Cvelbar, C. Canal, M. Hori. Editorial: Plasma-inspired biomaterials. J. Phys. D: Appl. Phys. 50 (2017) 040201 (4pp) doi:10.1088/1361-6463/50/4/040201.

  22. E. Gilabert-Chirivella, R. Perez, C. Ribeiro, S. Ribeiro, D.M. Correia, M.L. Gonzalez-Martin, J.M. Manero, S. Lanceros-Mendez, G. Gallego, J. Gómez. Chitosan patterning on titanium implants. Progress in Organic Coatings. Volume 111, October 2017, Pages 23–28. doi: doi.org/10.1016/j.porgcoat.2017.04.027.

  23. S. Lewin, A. Barba, C. Persson, J. Franch, M.P. Ginebra, C. Öhman-Mägi. Evaluation of bone formation in calcium phosphate scaffolds with μCT-method validation using SEM. Biomed. Mater. 12 (2017) 065005. doi: doi.org/10.1088/1748-605X/aa801d

  24. M. Herrero-Climent, M.M. Romero Ruiz, P. Lázaro Calvo, J.V. Ríos Santos, R.A. Perez, F.J Gil Mur. Effectiveness of a new dental implant bioactive surface: histological and histomorphometric comparative study in minipigs. Clin Oral Investig. 2017 Oct 12. doi: doi.org/10.1007/s00784-017-2223-y. ISSN: 1432-6981. Impact Factor: 2.207. Q1 21/89 Dentistry, Oral Surgery & Medicine.

  25. E. Velasco, L Monsalve-Guil, A. Jimenez, I. Ortiz, J.Moreno-Muñoz, E. Nuñez-Marquez, M. Pegueroles, R A. Pérez, F.J. Gil. Importance of the Roughness and Residual Stresses of Dental Implants on Fatigue and Osseointegration Behavior. In Vivo Study in Rabbits. Journal of Oral Implantology, Vol. XLII /No. Six /2016. doi: 10.1563/aaid-joi-D-16-00088.

  26. P.Sevilla, J.Gil, C.Aparicio. Relevant Properties for Immobilizing Short Peptides on Biosurfaces. IRBM 38(2017)256–265. doi: dx.doi.org/10.1016/j.irbm.2017.06.003. ISSN: 1959-0318.  



  1. C. Mas-Moruno, R. Fraioli, F. Rechenmacher, S. Neubauer, T. G. Kapp, H. Kessler. avb3- or a5b1-Integrin-Selective Peptidomimetics for Surface Coating. Angew. Chem. Int. Ed. 2016, 55, 7048 – 7067. doi: 10.1002/anie.201509782

  2. Z. Zhao, M. Espanol, J. Guillem-Marti, D. Kempf, A. Diez-Escudero, M.P. Ginebra. Ion-doping as a strategy to modulate hydroxyapatite nanoparticle internalization. Nanoscale, 2016, 8, 1595. doi: 10.1039/c5nr05262a

  3. M. Hoyos-Nogués, S. Brosel-Oliu, N. Abramova, F.X. Muñoz, A.Bratov, C. Mas-Moruno, F.J. Gil. Impedimetric antimicrobia lpeptide-based sensor for the early detection of periodontopathogenic bacteria. Biosensors and Bioelectronics86(2016)377–385. doi: dx.doi.org/10.1016/j.bios.2016.06.066

  4. M. Espanol, G. Mestres, Th. Luxbacher, J.B. Dory, M.P Ginebra. Impact of Porosity and Electrolyte Composition on the Surface Charge of Hydroxyapatite Biomaterials. ACS Appl. Mater. Interfaces, 2016, 8 (1), pp 908–917. doi: 10.1021/acsami.5b10404

  5. C. Herranz-Diez, C. Mas-Moruno, S. Neubauer, H. Kessler, F.J. Gil, M. Pegueroles, J.M. Manero, J. Guillem-Marti. Tuning mesenchymal stem cell response onto titanium-niobium-hafnium alloy by recombinant fibronectin fragments. ACS Appl. Mater. Interfaces, 2016, 8 (4), pp 2517-2525. doi: 10.1021/acsami.5b09576

  6. R. Fraioli, K. Dashnyam, J.H. Kim, R.A. Perez, H.W. Kim, J. Gil, M.P. Ginebra, J.M. Manero, C. Mas-Moruno. Surface guidance of stem cell behavior: Chemically tailored co-presentation of integrin-binding peptides stimulates osteogenic differentiation in vitro and bone formation in vivo. Acta Biomaterialia 43 (2016) 269–281. doi: dx.doi.org/10.1016/j.actbio.2016.07.049

  7. H. Aubin, C. Mas-Moruno, M. Iijima, N. Schütterle, M. Steinbrink, Assmann, F.J. Gil, A. Lichtenberg, M. Pegueroles, P. Akhyari. Customized Interface Biofunctionalization of Decellularized Extracellular Matrix: Toward Enhanced Endothelialization. Tissue Engineering: Part C, Volume 22, Number 5, 2016. DOI: 10.1089/ten.tec.2015.0556

  8. C. Canal, M. Modic, U. Cvelbarc, M.P. Ginebra. Regulating the antibiotic drug release from β-tricalcium phosphate ceramics by atmospheric plasma surface engineering. Biomater. Sci., 2016, 4, 1454. doi: 10.1039/c6bm00411c

  9. C. Canal, K. Khurana, S. Gallinetti, S. Bhatt, J. Pulpytel, F Arefi-Khonsari, M.P. Ginebra. Design of Calcium Phosphate Scaffolds with controlled Simvastatin release by Plasma polymerization. Polymer, v.92, 2016, pp.170-178. doi: 10.1016/j.polymer. 2016.03.069

  10. Maria Godoy-Gallardo, Jordi Guillem-Marti, Pablo Sevilla, José M. Manero, Francisco J. Gil, Daniel Rodriguez. Anhydride-functional silane immobilized onto titaniumsurfaces induces osteoblast cell differentiation and reduces bacterial adhesion and biofilm formation. Materials Science and Engineering C 59 (2016) 524-532. http://dx.doi.org/10.1016/j.msec.2015.10.051

  11. G. Mestres, K. Kugiejko, D. Pastorino, J.Unosson, C. Öhman, M. Karlsson Ott, M.-P. Ginebra, C. Persson. Changes in the drug release pattern of fresh and set simvastatin-loaded. Materials Science and Engineering C 58(2016) 88-96. http://dx.doi.org/10.1016/j.msec.2015.08.016

  12. Godoy-Gallardo M., Manzanares-Céspedes M.C., Sevilla P., Nart J., Manzanares N., Manero J.M., Gil F.J., Boyd S.K., Rodríguez D., Evaluation of bone loss in antibacterial coated dental implants: An experimental study in dogs. Materials Science and Engineering C 69 (2016) 538–545. doi:10.1016/j.msec.2016.07.020.

  13. J. Luo, I. Ajaxon, M.P. Ginebra, H. Engqvist, C. Persson. Compressive, diametral tensile and biaxial flexural strength of cutting-edge calcium phosphate cements. Journal of the Mechanical Behavior of Biomedical Materials 60(2016) 617-27. doi: dx.doi.org/10.1016/j.jmbbm.2016.03.028. 

  14. M. Hamed Misbah, M. Espanol, L. Quintanilla, M.P. Ginebra, J.C. Rodríguez-Cabello. Formation of calcium phosphate nanostructures under the influence of self-assembling hybrid elastin-like-statherin recombinamers. RSC Adv., 2016, 6, 31225-31234. doi: 10.1039/x0xx00000x.

  15. Sevilla, P.; Vining, K.; Dotor, J.; Rodriguez, D.; Gil, F.J.; Aparicio, C.. Surface immobilization and bioactivity of TGF-ß1 inhibitor peptides for bone implant applications. Journal of biomedical materials research. Part B, Applied biomaterials. Volume 104, Issue 2, 1 February 2016, Pages 385-394. doi: 10.1002/jbm.b.33374. 

  16. J. Unosson, E. B. Montufar, H. Engqvist, M.P. Ginebra, C. Persson. Brushite foams - the effect of Tween® 80 and Pluronic® F-127 on foam porosity and mechanical properties. J Biomed Mater Res B Appl Biomater. 2016 Jan;104(1):67-77. doi: 10.1002/jbm.b.33355

  17. C. Labay, J. Buxadera-Palomero, M. Avilés, C. Canal, M.P. Ginebra. Modulation of release kinetics by plasma polymerization of ampicillin-loaded β-TCP ceramics. J. Phys. D: Appl. Phys. 49 (2016) 304004 (10pp). doi:10.1088/0022-3727/49/30/304004

  18. E. Rupérez, J.M. Manero, L.A. Bravo-González, E. Espinar, F.J. Gil. Development of Biomimetic NiTi Alloy: Influence of Thermo-Chemical Treatment on the Physical, Mechanical and Biological Behavior. Materials 2016, 9, 402. doi:10.3390/ma9060402

  19. A. Rodríguez-Contreras, M. S. Marqués-Calvo, F.J. Gil, J.M. Manero. Modification of titanium surfaces by adding antibiotic-loaded PHB spheres and PEG for biomedical applications. J Mater Sci: Mater Med (2016) 27:124. doi: 10.1007/s10856-016-5723-4.

  20. C. Caparrós, M. Ortiz-Hernandez, M. Molmeneu, M. Punset, J.A. Calero, C. Aparicio, M. Fernández-Fairén, R. Perez, F.J. Gil. Bioactive macroporous titanium implants highly interconnected. J Mater Sci: Mater Med (2016) 27:151. doi: 10.1007/s10856-016-5764-8.

  21. R. O'Neill, E. B. Montufar, M.P. Ginebra, I. Wilson, A. Lennon, N. Dunne. Extent and Mechanism of Phase Separation during the Extrusion of Calcium Phosphate Pastes. Journal of Materials Science. Materials in Medicine, 2016 Feb;27(2):29. doi: 10.1007/s10856-015-5615-z

  22. E. Espinar-Escalona, L.A. Bravo-Gonzalez, M. Pegueroles, F.J. Gil. Roughness and wettability effect on histological and mechanical response of self-drilling orthodontic mini-implants. Clin Oral Invest (2016) 20:1115–1120. doi: 10.1007/s00784-016-1770-y



  1. C. Labay, J.M. Canal, M. Modic, U. Cvelbar, M. Quiles, M. Armengol, M.A. Arbos, F.J. Gil, C. Canal. Antibiotic-loaded polypropylene surgical meshes with suitable biological behaviour by plasma functionalization and polymerization. Biomaterials 71 (2015) 132- doi: 10.1016/j.biomaterials.2015.08.023.144

  2. N. Marín-Pareja, M. Cantini, C. González-García, E. Salvagni, M. Salmerón-Sánchez, M.P. Ginebra. Different Organization of Type I Collagen Immobilized on Silanized and Nonsilanized Titanium Surfaces Affects Fibroblast Adhesion and Fibronectin Secretion. ACS Appl. Mater. Interfaces, 2015, 7 (37), pp 20667-20677. doi 10.1021/acsami.5b05420. ISSN 1944-8244. Impact Factor: 7.145. Q1 25/271 Materials Science, Multidisciplinary; Q1 14/83 Nanoscience & Nanotechnology.

  3. M. Godoy-Gallardo, Zh. Wang, Y. Shen, J.M. Manero, F.J. Gil, D. Rodriguez, M. Haapasalo. Antibacterial Coatings on Titanium Surfaces: A Comparison Study Between in Vitro Single-Species and Multispecies Biofilm. ACS Appl. Mater. Interfaces 2015, 7, 5992?6001. doi: 10.1021/acsami.5b00402

  4. D. Pastorino, C. Canal, M.P. Ginebra. Multiple characterization study on porosity and pore structure of calcium phosphate cements. Acta Biomaterialia (2015) 205-214, doi: 10.1016/j.actbio.2015.09.017

  5. D. Pastorino, C. Canal, M.P. Ginebra. Drug delivery from injectable calcium phosphate foams by tailoring the macroporosity-drug interaction. Acta Biomaterialia 12 (2015):250-9. doi: 10.1016/j.actbio.2014.10.031

  6. Kovtun, M.J. Goeckelmann, A.A. Niclas, E.B. Montufar, M.P. Ginebra, J.A. Planell, M. Santin, A. Ignatius. In vivo performance of novel soybean/gelatin-based bioactive and injectable hydroxyapatite foams. Acta Biomater. 12 (2015): 242-249. doi: 10.1016/j.actbio.2014.10.034

  7. E. Unosson, D. Rodriguez, K. Welch, H. Engqvist. Reactive combinatorial synthesis and characterization of a gradient Ag-Ti oxide thin film with antibacterial properties. Acta Biomater 2015 Jan 1;11:503-10. doi: 10.1016/j.actbio.2014.09.048

  8. P. Rocas, M. Hoyos-Nogués, J. Rocas, J.M. Manero, J. Gil, F. Albericio, C. Mas-Moruno. Installing multifunctionality on titanium with RGD-decorated polyurethane-polyurea roxithromycin loaded nanoparticles: toward new osseointegrative therapies. Adv Healthc Mater. 2015 Sep 16;4(13):1956-60. doi: 10.1002/adhm.201500245

  9. Godoy-Gallardo, M., Mas-Moruno, C., Yu, K., Manero, J.M., Gil, F.J., Kizhakkedathu, J., Rodriguez, D. Antibacterial Properties of hLf1-11 Peptide onto Titanium Surfaces: A Comparison Study Between Silanization and Surface Initiated Polymerization. Biomacromolecules. 16 (2015):483-96. doi: 10.1021/bm501528x

  10. E. Rupérez, J.M. Manero, K. Riccardi, Yuping Li, C. Aparicio, F.J. Gil. Development of tantalum scaffold for orthopedic applications produced by space-holder method. Materials & Design 83 (2015) 112-119. doi: http://dx.doi.org/10.1016/ j.matdes.2015.05.067

  11. R. Fraioli, F. Rechenmacher, S. Neubauer, J.M. Manero, J. Gil, H Kessler, C. Mas-Moruno. Mimicking bone extracellular matrix: Integrin-bindingpeptidomimetics enhance osteoblast-like cells adhesion,proliferation, and differentiation on titanium. Colloids and Surfaces B: Biointerfaces. 128, 2015, 191-200. doi:10.1016/j.colsurfb.2014.12.057

  12. C. Herranz-Diez, Q. Li, C. Lamprecht, C. Mas-Moruno, S. Neubauer, H. Kessler, J.M. Manero, J. Guillem-Martí, C. Selhuber-Unkel. Bioactive compounds immobilized on Ti and TiNbHf: AFM-basedinvestigations of biofunctionalization efficiency and cell adhesion. Colloids and Surfaces B: Biointerfaces 136 (2015) 704-711. http://dx.doi.org/10.1016/j.colsurfb. 2015.10.008

  13. M.I. Castellanos, A-S. Zenses, A. Grau, J.C. Rodríguez-Cabello, F.J Gil, J.M. Manero, M. Pegueroles. Biofunctionalization of REDV elastin-like recombinamers improves endothelialization on CoCr alloy surfaces for cardiovascular applications. Colloids and Surfaces B: Biointerfaces 127 (2015) 22-32. doi: 10.1016/j.colsurfb.2014.12.056

  14. S. Lee, H. Yun, R.A. Perez, S. Gallinetti, M. Ginebra, S. Choi, E. Kim and H. Kim. Nanotopological-Tailored Calcium Phosphate Cements for the Odontogenic Stimulation of Human Dental Pulp Stem Cells through Integrin Signaling. RSC Adv., 2015, 5, 63363. doi: 10.1039/C5RA11564G

  15. E.Cuzmar, R.A. Perez, M.C. Manzanares, M.P.Ginebra, J.Franch. In vivo osteogenic potential of biomimetic hydroxyapatite/collagen microspheres: comparison with injectable cement pastes. PLoS One. 2015 Jul 1;10(7):e0131188. doi: 10.1371/journal.pone.0131188

  16. G. Mestres, M. Espanol, W. Xia, C. Persson, M.P Ginebra, M. Karlsson Ott. Inflammatory Response to Nano and Microstructured Hydroxyapatite. PLoS ONE 10(4): e0120381 (2015). doi:10.1371/journal.pone.0120381

  17. J. Guillem-Marti, C. Herran-Diez, J.E. Shaffer, F.J. Gil, J.M. Manero. Mechanical and microstructural characterization of new nickel-free low modulus β-type titanium wires during thermomechanical treatments. Materials Science and Engineering A 636 (2015) 507-515. doi:10.1016/j.msea.2015.03.060

  18. C. Mas-Moruno, B. Garrido, D. Rodriguez, E. Ruperez, F.J. Gil. Biofunctionalization strategies on tantalum-based materials for osseointegrative applications. J Mater Sci: Mater Med (2015) 26:109. doi: 10.1007/s10856-015-5445-z

  19. B. Bullon, E.F. Bueno, M. Herrero, A. Fernandez-Palacin, J.V. Rios, P. Bullon, F.J. Gil. Effect of irrigation and stainless steel drills on dental implant bed heat generation. J Mater Sci: Mater Med (2015) 26:75. doi: 10.1007/s10856-015-5412-8

  20. C. Öhman, J. Unosson, E. Carlsson, M.P. Ginebra, C. Persson, H. Engqvist. Porosity prediction of calcium phosphate cements based on chemical composition. J Mater Sci Mater Med. 2015 Jul;26(7):210

  21. D. Martin-Gili, M. Molmeneu, M. Fernandez, M. Punset, Ll. Giner, J. Armengou, F. Javier Gil. Determination of fluid leakages in the different screw-retained implant-abutment connections in a mechanical artificial mouth. J Mater Sci Mater Med. 2015 Jul;26(7):211. doi: 10.1007/s10856-015-5544-x

  22. J. Buxadera-Palomero, C. Canal, S. Torrent-Camarero, B. Garrido, F.J. Gil, D. Rodríguez. Antifouling coatings for dental implants: Polyethylene glycol-like coatings on titanium by plasma polymerization. Biointerphases (2015); 10(2):029505. doi: 10.1116/1.4913376

  23. E. Fernandez-Garcia, J. Guillem-Marti, C.F. Gutierrez-Gonzalez, A. Fernandez, M.P. Ginebra, S.Lopez-Esteban. Osteoblastic cell response to spark plasma-sintered zirconia/titanium cermets. J Biomater Appl. 2015 Jan;29(6):813-23. doi: 10.1177/0885328214547400

  24. C. Persson, E. Robert, E. Carlsson, C. Robo, A. López, M. Godoy-Gallardo, M.P. Ginebra, H. Engqvist. The effect of unsaturated fatty acid and triglyceride oil addition on the mechanical and antibacterial properties of acrylic bone cements. J Biomater Appl. 2015 Sep;30(3):279-89. doi: 10.1177/0885328215581316

  25. Ajaxon, Y. Maazouz, M.P. Ginebra, C. Öhman, C. Persson. Evaluation of a porosity measurement method for wet calcium phosphate cements. J Biomater Appl. 2015 Nov;30(5):526-36. doi: 10.1177/0885328215594293

  26. C. Herranz-Diez, F.J. Gil, J. Guillem-Marti, J.M. Manero. Mechanical and physicochemical characterization along with biological interactions of a new Ti25Nb21Hf alloy for bone tissue engineering. Journal of Biomaterials Applications 30(2) 171-181. doi: 10.1177/0885328215577524



  1. C. Mas-Moruno, R. Fraioli, F. Albericio, JM. Manero, FJ. Gil. A novel peptide-based platform for the dual presentation of biologically-active peptide motifs on biomaterials. ACS Appl Mater Interfaces. 6 (2014):6525-36. doi: 10.1021/am5001213

  2. M. Godoy-Gallardo, C. Mas-Moruno, M. C. Fernández-Calderón, C. Pérez-Giraldo, J.M. Manero, F. Albericio, F.J. Gil, D. Rodriguez. Covalent Immobilization of hLf1-11 Peptide onto Titanium Surface Reduces Bacterial Adhesion and Biofilm Formation. Acta Biomaterialia. 10(2014):3522-34. doi: 10.1016/j.actbio.2014.03.026

  3. Y. Maazouz, E.B. Montufar, J. Guillem-Marti, I. Fleps, C. Öhman, C. Persson, M.P. Ginebra. Robocasting of biomimetic hydroxyapatite scaffolds using self-setting inks. J Mater Chem B. 2014, 2, 5378-86. doi: 10.1039/C4TB00438H

  4. M. Espanol, Z. Zhao, J. Almunia, M.P. Ginebra. Calcium phosphate neuron-like structures: a rare case or a common structure? J. Mater. Chem. B, 2014, 2 (14), 2020-2029. doi: 10.1039/C3TB21524E

  5. E. Veronesi, A. Murgia, A. Caselli, G. Grisendi, M.S. Piccinno, V.Rasini, R. Giordano, T. Montemurro, P. Bourin, L. Sensebè, M.T. Rojewski, H. Schrezenmeier, P. Layrolle, M.P. Ginebra, C. Bunu Panaitescu, E. Gómez-Barrena, F. Catani, P. Paolucci, J.S. Burns, M. Dominici. Transportation Conditions for Prompt Use of Ex-vivo Expanded Freshly Harvested Clinical Grade MSC For Bone Regeneration. Tissue Engineering A 20 (2014) 239-251, doi:10.1089/ten.tec.2013.0250. doi: 10.1089/ten.TEC.2013.0250

  6. E. Salvagni, G. Berguig, E. Engel, J.C. Rodriguez-Cabello, G.S. Coullerez, M. Textor, J.A. Planell, F.J. Gil, C. Aparicio. A Bioactive Elastin-like Recombinamer Reduces Unspecific Protein Adsorption and Enhances Cell Response on Titanium Surfaces. Colloids Surf B Biointerfaces. 114 (2014):225-33. doi: 10.1016/j.colsurfb.2013.10.008

  7. N. Marín-Pareja, E. Salvagni, J. Guillem-Marti, C. Aparicio, M.P. Ginebra. Collagen-functionalised titanium surfaces for biological sealing of dental implants: effect of immobilisation process on fibroblasts response. Colloids Surf B Biointerfaces. 2014 Oct 1;122:601-10. doi: 10.1016/j.colsurfb.2014.07.038

  8. M. Godoy-Gallardo, A.G. Rodríguez-Hernandez, L.M. Delgado, J.M. Manero, F.J. Gil, D. Rodríguez. Silver deposition on titanium surface by electrochemical anodizing process reduces bacterial adhesion of Streptococcus sanguinis and Lactobacillus salivarius. Clin. Oral Impl. Res. 0, 2014 / 1-10. doi: 10.1111/clr.12422

  9. Gil, FJ., Espinar, E., Llamas, JM., Sevilla, P. Fatigue life of bioactive titanium dental implants treated by means of Grit Blasting and Thermo-Chemical treatment. Clinical Implant Dentistry and Related Research. 16 (2014), 273-281. doi: 10.1111/j.1708-8208.2012.00468.x

  10. C. Caparros, J. Guillem-Martí, M. Punset, M. Molmeneu, J. Calero, FJ. Gil. Mechanical properties and in vitro biological response to porous titanium alloys for intervertebrae implants. Journal of the Mechanical Behavior of Biomedical Materials. 39, 2014; 79-86. doi: 10.1016/j.jmbbm.2014.05.029

  11. E. S. Sanzana, M. Navarro, M. P. Ginebra, J. A. Planell, H. A. Montecinos, A. C. Ojeda, V. A. Contreras. Role of porosity and pore architecture in the in vivo bone regeneration capacity of biodegradable glass scaffolds. J Biomed Mater Res A 102A (2014):1767-73. doi: 10.1002/jbm.a.34845

  12. M. González, J. Peña, F.J. Gil, J.M. Manero. Low modulus Ti-Nb-Hf alloy for biomedical applications. Materials Science and Engineering C 42 (2014) 691-695. doi: 10.1016/j.msec.2014.06.010

  13. J.C. Valera, E. Espinar, JM. Llamas, JM. Manero, E. Ruperez, FJ. Gil. Mechanical Properties of a New Superelastic Polymer Orthodontic Archwire. Mater Sci Eng C Mater Biol Appl. 2014 Sep 1;42:1-6. doi: 10.1016/j.msec.2014.05.008

  14. G. Mestres, F. S. Aguilera, N. Manzanares, R. Osorio, M. Toledano, M.P. Ginebra. Magnesium phosphate cements for endodontic applications with improved long-term sealing ability. International Endodontic Journal, 47, 127-139, 2014. 12123. doi: 10.1111/iej.12123

  15. F. Rechenmacher, K. Steigerwald, B. Laufer, S. Neubauer, T. G. Kapp, L. Li, C. Mas-Moruno, M. Joner, H. Kessler. The Integrin Ligand c(RGDf(NMe)Nal) Reduces Neointimal Hyperplasia in a Polymer-Free Drug-Eluting Stent System. ChemMedChem. 2014 Jul;9(7):1413-8. doi: 10.1002/cmdc.201400078

  16. L. Morejón-Alonso, J.A. Delgado García-Menocal, M. Tarragó Aymerich, J. A. Alvarez Guichard, M. García-Vallés, S. Martínez Manent, M.P. Ginebra. Calcium Phosphate Glasses: Silanation process and effect on the bioactivity behavior of Glass-PMMA composites. J Biomed Mater Res B Appl Biomater. 102(2014):205-13. doi: 10.1002/jbm.b.32996

  17. V. Paredes, E. Salvagni, E. Rodríguez-Castellon, F. J. Gil, J. M. Manero. Study on the use of 3-aminopropyltriethoxysilane and 3-chloropropyltriethoxysilane to surface biochemical modification of a novel low elastic modulus Ti-Nb-Hf alloy. J Biomed Mater Res Part B: Appl Biomater. 2014 Jun 9. doi: 10.1002/jbm.b.33226

  18. C. Labay, J. M. Canal, A. Navarro, C. Canal. Corona plasma modification of PA 66 for the design of textile delivery systems for cosmetic therapy. Applied Surface Science (2014) 316:251-258. DOI: 10.1016/j.apsusc.2014.07.191

  19. S. Gallinetti, C. Canal, M. P. Ginebra. Development and Characterization of Biphasic Hydroxyapatite/b-TCP Cements. J. Am. Ceram. Soc., 1-9 (2014). doi:  10.1111/jace.12861

  20. FJ. Gil, M. Herrero, P. Lázaro, J.V. Rios. Implant-abutment connections: influence of the design on the microgap and their fatigue and fracture behavior of dental implants. Journal of Materials Science: Materials in Medicine. Volume 25, Issue 7 (2014), Page 1825-1830. doi: 10.1007/s10856-014-5211-7

  21. V. Paredes, E. Salvagni , E. Rodriguez, J. Gil, J.M. Manero. Assessment and comparison of surface chemical composition and oxide layer modification upon two different activation methods on a CoCrMo alloy. J Mater Sci Mater Med. 2014 Feb;25(2):311-20. doi: 10.1007/s10856-013-5083-2

  22. L.A. Bravo, A. González de Cabañes, JM. Manero, E. Rupérez, FJ. Gil. NiTi superelastic orthodontic archwires with polyamide coating. J Mater Sci Mater Med. 2014 Feb;25(2):555-60. doi: 10.1007/s10856-013-5070-7

  23. M. Dessì, M.A. Alvarez-Perez, R. De Santis, M.P. Ginebra, J.A. Planell, L. Ambrosio. Bioactivation of calcium deficient hydroxyapatite with foamed gelatin gel. A new injectable self-setting bone analogue. doi: 10.1007/s10856-013-5071-6. J Mater Sci Mater Med 25(2014):283-95. doi: 10.1007/s10856-013-5071-6

  24. C. Canal, S. Gallinetti, M.P. Ginebra. Low pressure plasma treatment of polylactide fibres for enhanced mechanical performance of fibre-reinforced calcium phosphate cements. Plasma Processes and Polymers 11 (2014), 694-703. doi: 10.1002/ppap.201400018

  25. FJ Gil, N. Manzanares, A. Badet, C. Aparicio, MP Ginebra. Biomimetic treatment on dental implants for short -term bone regeneration. Clin Oral Investig. 2014 Jan;18(1):59-66. doi: 10.1007/s00784-013-0953-z

  26. S. Manso, G. Mestres, M.P. Ginebra, N. De Belie, I. Segura, A. Aguado. Development of a low pH cementitious material to enlarge bioreceptivity. Construction and Building Materials 54 (2014): 485-495. doi:10.1016/j.conbuildmat.2014.01.001

  27. M. Fernández, L. Delgado, M. Molmeneu, D. García, D. Rodríguez. Analysis of the misfit of dental implant-supported prostheses made with three manufacturing processes. Journal Prosthet. Dent. 2014 Feb;111(2):116-23. doi: 10.1016/j.prosdent. 2013.09.006. ISSN: 0022-3913



  1. C. Canal, D. Pastorino, G. Mestres, Ph. Schuler, M.P. Ginebra. Relevance of microstructure for the early antibiotic release of fresh and pre-set calcium phosphate cements. Acta Biomaterialia 9 (2013) 8403-8412. doi:10.1016/j.actbio.2013.05.016

  2. E.B. Montufar, Y. Maazouz, M.P. Ginebra. Relevance of the setting reaction to the injectability of tricalcium phosphate pastes. Acta Biomaterialia 9 (2013):6188-98. doi: 10.1016/j.actbio.2012.11.028

  3. G. Mestres, M. Abdolhosseini, W. Bowles, S.H. Huang, C. Aparicio, S.U. Gorr, M.P. Ginebra. Antimicrobial properties and dentin bonding strength of magnesium phosphate cements. Acta Biomaterialia 9 (2013):8384-93. doi: 10.1016/j.actbio.2013.05.032

  4. R.A. Pérez, G. Altankov, E. Jorge-Herrero, M.P. Ginebra. Micro- and nanostructured hydroxyapatite-collagen microcarriers for bone tissue engineering applications. Journal of Tissue Engineering and Regenerative Medicine 7 (2013) 353-61. doi: 10.1002/term.530

  5. Chen, X., Sevilla, P., Aparicio. C. Surface biofunctionalization by covalent co-immobilization of  Oligopeptides. Colloids and Surfaces B: Biointerfaces 107 (2013) 189- 197. doi: 10.1016/j.colsurfb.2013.02.005

  6. Guillem-Marti, J., Delgado, L, Godoy-Gallardo, M., Pegueroles, M., Herrero, M., Gil, F. J. Fibroblast adhesion and activation onto micro-machined titanium surfaces. Clinical Oral Implants Research 24(2013):770-80. doi: 10.1111/j.1600-0501.2012.02451.x

  7. Rodríguez-Contreras, C. Canal, M. Calafell-Monfor, M.P. Ginebra G. Julio-Mora, M.S. Marqués-Calvo. Methods for the preparation of doxycycline-loaded phb micro- and nano-spheres. European Polymer Journal 49 (2013) 3501-3511. doi: 10.1016/j.eurpolymj.2013.08.010 

  8. Perez, R.A., Kim, T.H., Kim, M., Jang, J.H., Ginebra, M.P., Kim, H.W. Calcium Phosphate Cements Loaded with Basic Fibroblast Growth Factor: Delivery and In Vitro Cell Response. J Biomed Mater Res Part A (2013)101A:923-931. doi: 10.1002/jbm.a.34390

  9. Gonzalez, M., Salvagni, E., Rodriguez-Cabello, J.C., Ruperez, E., Gil, F.J., Peña, F.J., Manero, J.M. A low elastic modulus Ti-Nb-Hf alloy bioactivated with an elastin-like protein-based polymer enhances osteoblast cell adhesion and spreading. J Biomed Mater Res Part A 101(3):819-26 (2013). doi: 10.1002/jbm.a.34388 

  10. J. Briceño, A. Romeu, E. Espinar, J.M. Llamas, F.J. Gil. Influence of the microstructure on electrochemical corrosion and nickel release in NiTi orthodontic archwires. Materials Science and Engineering: C. Volume 33, Issue 8, 1 December 2013, 4989-4993. doi:10.1016/j.msec.2013.08.024

  11. M. Arciniegas, JM. Manero, E. Espinar, JM. Llamas, JM. Barrera, F.J. Gil. New Ni-free superelastic alloy for orthodontic applications. Materials Science and Engineering C 33 (2013) 3325-3328. doi:10.1016/j.msec.2013.04.014

  12. Labay, C., Canal, C., Rodriguez, C.C., Caballero, G., Canal, J.M. Plasma Surface Functionalization and Dyeing Kinetics of PAN-PMMA Copolymers. Applied Surface Science. 283 (2013) 269-275. doi:10.1016/j.apsusc.2013.06.100

  13. Abalos, C., Paul, A., Mendoza, A., Solano, E., Palazon, C., Gil, F.J. Influence of Soft Drinks with Low pH on Different Ni-Ti Orthodontic Archwire Surface Patterns. Journal of Materials Engineering and Performance.  Volume 22(3) March (2013)-759. doi: 10.1007/s11665-012-0311-3

  14. Herrero-Climent M, Lázaro P, Vicente Rios J, Lluch S, Marqués M, Guillem-Martí J, Gil FJ. Influence of acid-etching after grit-blasted on osseointegration of titanium dental implants: in vitro and in vivo studies. J Mater Sci Mater Med. (2013) Aug; 24(8):2047-55. doi: 10.1007/s10856-013-4935-0

  15. Arciniegas, M., Peña, J., Gil, FJ., Manero JM. In-vitro response of pre-osteoblastic MG63 cells on Ni-free Ti shape memory substrates. Journal of Biomedical Materials Research: Part B - Applied Biomaterials 101(5):709-20 (2013). doi: 10.1002/jbm.b.32873

  16. Perez, R.A., Ginebra, M.P. Injectable collagen/?-tricalcium phosphate cement: collagen-mineral phase interactions and cell response. J Mater Sci: Mater Med, (2013) Feb;24(2):381-93. doi: 10.1007/s10856-012-4799-8

  17. Rodríguez-Hernández, A., Espinar, E., Llamas, J.M. Barrera, J.M., Gil, F.J. Alumina shot-blasted particles on commercially pure titanium surfaces prevent bacterial attachment. Materials Letters 92 (2013) 42-44. doi:10.1016/j.matlet.2012.10.022

  18. F.J. Gil, M. Cenizo, E. Espinar, A. Rodriguez, E. Rúperez, J.M. Manero. NiTi superelastic orthodontic wires with variable stress obtained by ageing treatments. Materials Letters 104 (2013)5-7. doi:10.1016/j.matlet.2013.03.135

  19. Varela, J.C., Velo, M., Espinar, E., Llamas, J.M., Gil, F.J. Obtention and characterization of new superelastic polymer for biomedical applications. Comparison with NiTi and NiTiCu alloys. Materials Letters. 92 (2013) 49-51. doi:10.1016/j.matlet.2012.10.028

  20. M. López-Cano, M. Armengol, M.T. Quiles, A. Biel, J. Velasco, P. Huguet, A. Mestre, L. M. Delgado, F. X. Gil, M.A. Arbós. Preventive midline laparotomy closure with a new bioabsorbable mesh: An experimental study. Journal of Surgical Research 181 (2013) 160-169. doi: 10.1016/j.jss.2012.05.041

  21. E. Espinar, J.M. Llamas, JM. Barrera, C. Abalos, FJ. Gil. Effect of temperature on the orthodontic clinical applications of NiTi closed-coil springs. Med Oral Patol Oral Cir Bucal. 2013 Jul; 18(4): e721-e724. doi: 10.4317/medoral.19073

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