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BBT's Publications during the last 5 years


  1. C. García-Mintegui, L. C. Cordoba, J. Buxadera-Palomero, A. Marquina, E. Jimenez-Pique, M.P. Ginebra, J.L. Cortina, M. Pegueroles. Zn-Mg and Zn-Cu alloys for stenting applications: From nanoscale mechanical characterization to in vitro degradation and biocompatibility. Bioactive Materials Volume 6, Issue 12, December 2021, Pages 4430-4446. doi:

  2. J. Tornin, C. Labay, F. Tampieri, M.P. Ginebra, C. Canal. Evaluation of the effects of cold atmospheric plasma and plasma-treated liquids in cancer cell cultures. Nature Protocols volume 16, pages2826–2850 (2021). doi: 

  3. Y. Raymond, E. Thorel, M. Liversain, A. Riveiro, J. Pou, M.P. Ginebra. 3D printing non-cylindrical strands: Morphological and structural implications. Additive Manufacturing, Volume 46, 2021, 102129. doi:

  4. V. Chausse, R. Schieber, Y. Raymond, B. Ségry, R. Sabaté, K. Kolandaivelu, M.P. Ginebra, M. Pegueroles. Solvent-cast direct-writing as a fabrication strategy for radiopaque stents. Additive Manufacturing, Volume 48, Part B, 2021, 102392. doi:

  5. O. Estupiñán, E. Niza, I. Bravo, V. Rey, J. Tornín, B. Gallego, P. Clemente-Casares, F. Moris, A. Ocaña, V. Blanco-Lorenzo, M.Rodríguez-Santamaría, A. Vallina-Álvarez, M.V. González, A. Rodríguez, D. Hermida-Merino, C. Alonso-Moreno, R. Rodríguez. Mithramycin delivery systems to develop effective therapies in sarcomas. Journal of Nanobiotechnology. 2021 Sep 6;19(1):267. doi: 10.1186/s12951-021-01008-x.

  6. A. Serrà, J. García-Torres. Electrochemistry: A basic and powerful tool for micro- and nanomotor fabrication and characterization. Applied Materials Today, Volume 22, 2021, 100939. doi:

  7. A. Puiggalí-Jou, I. Babeli, J.J. Roa, J.O. Zoppe, J. Garcia-Amorós, M.P Ginebra, C. Alemán, J. García-Torres. Remote Spatiotemporal Control of a Magnetic and Electroconductive Hydrogel Network via Magnetic Fields for Soft
    Electronic Applications. ACS Appl. Mater. Interfaces 2021, 13, 36, 42486–42501. doi:

  8. I. Lodoso-Torrecilla, J.J.J.P. van den Beucken, J.A. Jansen. Calcium phosphate cements: Optimization toward biodegradability. Acta Biomater. 2021 Jan 1;119:1-12. doi: 10.1016/j.actbio.2020.10.013.

  9. J. Konka, J. Buxadera-Palomero, M. Espanol, M.P. Ginebra. 3D printing of hierarchical porous biomimetic hydroxyapatite scaffolds: Adding concavities to the convex filaments. Acta Biomaterialia Volume 134, 15 October 2021, Pages 744-759. doi:

  10. Y. Raymond, M. Bonany, C. Lehmann, E. Thorel, R. Benítez, J. Franch, M. Espanol, X. Solé-Martí, M.C. Manzanares, C. Canal, M.P. Ginebra. Hydrothermal processing of 3D-printed calcium phosphate scaffolds enhances bone formation in vivo: a comparison with biomimetic treatment. Acta Biomateriaia Volume 135, November 2021, Pages 671-688. doi:

  11. M.Á. Brennan, D.S. Monahan, B. Brulin, S. Gallinetti, P. lHumbert, Ch. Tringides, C. Canal, M.P. Ginebra, P. Layrolle. Biomimetic versus sintered macroporous calcium phosphate scaffolds enhanced bone regeneration and human mesenchymal stromal cell engraftment in calvarial defects. Acta Biomaterialia Volume 135, November 2021, Pages 689-704. doi:

  12. A. Rodriguez-Contreras, M. Punset, J.A. Calero, F.J. Gil, E. Ruperez, J.M. Manero. Powder metallurgy with space holder for porous titanium implants: A review. Journal of Materials Science & Technology Volume 76, 20 June 2021, Pages 129-149. doi: 

  13. J. Tornín, A. Villasante, X. Solé-Martí, M.P. Ginebra, C. Canal. Osteosarcoma tissue-engineered model challenges oxidative stress therapy revealing promoted cancer stem cell properties. Free Radical Biology and Medicine 164 (2021) 107–118. doi:

  14. J. Minguela, D.W. Müller, F. Mücklich, L. Llanes, M.P. Ginebra, J.J. Roa, C. Mas-Moruno. Peptidic biofunctionalization of laser patterned dental zirconia: A biochemical-topographical approach. Materials Science and Engineering: C, Volume 125, June 2021, 112096. doi:

  15. F. Tampieri, M.P. Ginebra, C. Canal. Quantification of Plasma-Produced Hydroxyl Radicals in Solution and their Dependence on the pH. Anal. Chem., 2021. DOI: 10.1021/acs.analchem.0c04906.

  16. X. Solé-Martí, A. Espona-Noguera, M.P Ginebra, C. Canal. Plasma-Conditioned Liquids as Anticancer Therapies In Vivo: Current State and Future Directions. Cancers 2021, 13(3), 452; doi:

  17. H. Martin-Gomez, Ll. Oliver-Cervello, I. Sanchez-Campillo, V. Marchan, M.P. Ginebra, C. Mas-Moruno. A versatile click chemistry-based approach for functionalizing biomaterials of diverse nature with bioactive peptides. Chem. Commun., 2021,57, 982-985. doi: 10.1039/d0cc07463b.

  18. I. Babeli, G. Ruano, A. Puiggalí‐Jou, M.P. Ginebra, C. Alemán, J. Garcia‐Torres. Self‐Healable and Eco‐Friendly Hydrogels for Flexible Supercapacitors. Adv. Sustainable Syst. 2021, 2000273. doi: 10.1002/adsu.202000273.

  19. L. Del-Mazo-Barbara, M.P. Ginebra. Rheological characterisation of ceramic inks for 3D direct ink writing: a review. Journal of the European Ceramic Society Volume 41, Issue 16, December 2021, Pages 18-33. doi:

  20. G. Boix-Lemonche, J. Guillem-Marti, M. Lekka, F. D'Este, F. Guida, J.M. Manero, B. Skerlavaj. Membrane perturbation, altered morphology and killing of Staphylococcus epidermidis upon contact with a cytocompatible peptide-based antibacterial surface. Colloids and Surfaces B: Biointerfaces 203 (2021) 111745. doi:

  21. I. Hamouda, C. Labay, U. Cvelbar, MP. Ginebra, C. Canal. Selectivity of direct plasma treatment and plasma‑conditioned media in bone cancer cell lines. Scientific Reports (2021) 11:17521. doi:

  22. M. Mateu-Sanz, J. Tornín, M.P. Ginebra, C. Canal. Cold Atmospheric Plasma: A New Strategy Based Primarily on Oxidative Stress for Osteosarcoma Therapy. J. Clin. Med. 2021, 10, 893. doi:

  23. T. Martinez, M. Español, C. Charvillat, O. Marsan, M.P. Ginebra, C. Rey, S. Sarda. a-tricalcium phosphate synthesis from amorphous calcium phosphate: structural characterization and hydraulic reactivity. J Mater Sci (2021) 56:13509–13523. doi:

  24. E. Vidal, J. Guillem-Marti, M.P. Ginebra, Ch. Combes, E. Ruperez, D. Rodriguez. Multifunctional homogeneous calcium phosphate coatings: Toward antibacterial and cell adhesive titanium scaffolds. Surface and Coatings Technology, Volume 405, 15 January 2021, 126557. doi: 

  25. J. Orrit-Prat, R. Bonet, E. Rupérez, M. Punset, M. Ortiz-Hernández, J. Guillem-Marti, A. Lousa, D. Cano, C. Díaz, G. García Fuentes, J. Caro. Bactericidal silver-doped DLC coatings obtained by pulsed filtered cathodic arc co-deposition. Surface and Coatings Technology, Volume 411, 15 April 2021, 126977. doi:

  26. A. Rodríguez-Contreras, D. Torres, B. Rafik, M. Ortiz-Hernandez, M.P. Ginebra, J. A. Calero, J.M Manero, E. Ruperez. Bioactivity and antibacterial properties of calcium- and silver-doped coatings on 3D printed titanium scaffolds. Surface & Coatings Technology 421 (2021) 127476. doi:

  27. J. Toledano-Serrabona, M.A. Sánchez-Garcés, C. Gay-Escoda, E. Valmaseda-Castellón, O. Camps-Font, P. Verdeguer, M. Molmeneu, F.J. Gil. Mechanical Properties and Corrosion Behavior of Ti6Al4V Particles Obtained by Implantoplasty: An In Vitro Study. Part II. Materials 2021, 14, 6519. doi:

  28. Y. Raymond, D. Pastorino, I. Ginebreda, Y. Maazouz, M. Ortiz, M.C. Manzanares, M.P. Ginebra. Computed tomography and histological evaluation of xenogenic and biomimetic bone grafts in three-wall alveolar defects in minipigs. Clin Oral Invest (2021). doi:

  29. M. Punset, J. Villarrasa, J. Nart, J.M. Manero, B. Bosch, R. Padrós, R.A. Perez, F.J. Gil. Citric Acid Passivation of Titanium Dental Implants for Minimizing Bacterial Colonization Impact. Coatings 2021, 11, 214. doi:

  30. D. Boehm, C. Canal. Application of Plasma Technology in Bioscience and Biomedicine. Appl. Sci. 2021, 11(16), 7203. doi:

  31. J. Buxadera-Palomero, K. Fricke, S. Reuter, F.J. Gil, D. Rodriguez, C. Canal. One-Step Liquid Phase Polymerization of HEMA by Atmospheric-Pressure Plasma Discharges for Ti Dental Implants. Appl. Sci. 2021, 11, 662. doi:

  32. R. Schieber, Y. Raymond, C. Caparrós, J. Bou, E. Herrero Acero, G.M. Guebitz, C. Canal, M. Pegueroles. Functionalization Strategies and Fabrication of Solvent-Cast PLLA for Bioresorbable Stents. Appl. Sci. 2021, 11, 1478. doi: 

  33. F. Arias-González, A. Rodríguez-Contreras, M. Punset, J.M. Manero, O. Barro, M. Fernández-Arias, F. Lusquiños, F.J. Gil, J. Pou. In-Situ Laser Directed Energy Deposition of Biomedical Ti-Nb and Ti-Zr-Nb Alloys from Elemental Powders. Metals 2021, 11, 1205. doi:

  34. Ll. Oliver-Cervello, H. Martin-Gomez, C. Mas-Moruno. New trends in the development of multifunctional peptides tofunctionalize biomaterials. J Pep Sci. 2021;e3335. doi:



  1. O. Hakimi, M. Krallinger, M.P. Ginebra. Time to kick-start text mining for biomaterials. Nat Rev Mater (2020). doi:

  2. O. Hakimi, J.L. Gelpi, M. Krallinger, F. Curi, D. Repchevsky, M.P. Ginebra. The Devices, Experimental Scaffolds, and Biomaterials Ontology (DEB): A Tool for Mapping, Annotation, and Analysis of Biomaterials' Data. Adv. Funct. Mater. 2020, 1909910. doi: 10.1002/adfm.201909910.

  3. Ll. Oliver-Cervelló, H. Martin-Gómez, L. Reyes, F. Noureddine, E.A. Cavalcanti-Adam, M.P. Ginebra, C. Mas-Moruno. An Engineered Biomimetic Peptide Regulates Cell Behavior by Synergistic Integrin and Growth Factor Signaling. Adv. Heathcare Mat. 2020, 2001757. doi:

  4. C. Labay, M. Roldán, F. Tampieri, A. Stancampiano, P. Escot Bocanegra, M.-P. Ginebra, C. Canal, Enhanced Generation of Reactive Species by Cold Plasma in Gelatin Solutions for Selective Cancer Cell Death, ACS Appl. Mater. Interfaces, 2020, 12, 42, 47256–47269. doi:

  5. P. Kazimierczak, A. Benko, K. Palka, C. Canal, D. Kolodynska, A. Przekora. Novel synthesis method combining a foaming agent with freeze-drying to obtain hybrid highly macroporous bone scaffolds. Journal of Materials Science & Technology, Volume 43, 15 April 2020, Pages 52-63. doi:

  6. I. Babeli, G. Ruano, J. Casanovas, M.P. Ginebra. García-Torres, C. Alemán. Conductive, self-healable and reusable poly(3,4-ethylenedioxythiophene)-based hydrogels for highly sensitive pressure arrays.                J. Mater. Chem. C, 2020,8, 8654-8667. doi: 10.1039/d0tc01947j.

  7. M. Mateu-Sanz, J Tornín, B. Brulin, A. Khlyustova, M.P. Ginebra , P. Layrolle, C. Canal. Cold Plasma-Treated Ringer's Saline: A Weapon to Target Osteosarcoma, Cancers 2020, Vol. 12, Page 227, vol. 12, no. 1, p. 227 doi: 10.3390/cancers12010227.

  8. J. Sadowska, M.P.Ginebra. Inflammation and biomaterials: role of the immune response in bone regeneration by inorganic scaffolds. J Mater Chem B. 2020 Oct 28;8(41):9404-9427. doi: 10.1039/d0tb01379j.

  9. A. Przekora, M. Audemar, J. Pawlat, C, Canal, J.S. Thomann, C. Labay, M. Wojcik, M. Kwiatkowski, P. Terebun, G. Ginalska, S. Hermans, D. Duday. Positive Effect of Cold Atmospheric Nitrogen Plasma on the Behavior of Mesenchymal Stem Cells Cultured on a Bone Scaffold Containing Iron Oxide-Loaded Silica Nanoparticles Catalyst. Int. J. Mol. Sci. 2020, 21, 4738; doi:10.3390/ijms21134738.

  10. J. Camilleri, T. Arias Moliz, A. Bettencourt, J. Costa, F. Martins, D. Rabadijeva, D. Rodriguez, L. Visai, C. Combes, C. Farrugia,P. Koidis, C. Neves. Standardization of antimicrobial testing ofdental devices. Dental Materials Volume 36, Issue 3, March 2020, Pages e59-e73. doi:

  11. J. Minguela, S. Slawik, F. Mücklich, M.P. Ginebra, L. Llanes, C. Mas-Morunoa, J.J. Roa. Evolution of microstructure and residual stresses in gradually ground/polished 3Y-TZP. Journal of the European Ceramic Society 40 (2020) 1582–1591. doi:

  12. J. Minguela, M.P. Ginebra, L. Llanes, C. Mas-Moruno, J.J. Roa. Influence of grinding/polishing on the mechanical, phase stability and cell adhesion properties of yttria-stabilized zirconia. Journal of the European Ceramic Society, Volume 40, Issue 12, September 2020, Pages 4304-4314. doi://

  13. A. Puiggalí-Jou, E. Cazorla, G. Ruano, I. Babeli, M.P. Ginebra, J. García-Torres, C. Aleman. Electroresponsive Alginate-Based Hydrogels for Controlled Release of Hydrophobic Drugs. ACS Biomater. Sci. Eng. 2020, 6, 6228−6240. doi:

  14. I. Hamouda, C.Labay, M.P. Ginebra, E. Nicol, C. Canal. Investigating the atmospheric pressure plasma jet modification of a photo-crosslinkable hydrogel, Polymer, Volume 192, 27 March 2020, 122308. doi:

  15. L. Vidal, C. Kampleitner, S. Krissian, M.A. Brennan, O. Hoffmann, Y. Raymond, Y. Maazouz, M.P. Ginebra, P. Rosset, P. Layrolle. Regeneration of segmental defects in metatarsus of sheep with vascularized and customized 3D-printed calcium phosphate scaffolds. Scientific Reports (2020) 10:7068 |

  16. J. Buxadera-Palomero, M. Godoy-Gallardo, M. Molmeneu, M. Punset, F.J. Gil. Antibacterial Properties of Triethoxysilylpropyl Succinic Anhydride Silane (TESPSA) on Titanium Dental Implants. Polymers 2020, 12(4), 773. doi:

  17. A. Rodríguez-Contreras, D. Torres,c, J. Guillem-Marti, P. Sereno, M.P. Ginebra, J.A. Calero, J.M. Manero, E. Rupérez. Development of novel dual-action coatings with osteoinductive and antibacterial properties for 3D-printed titanium implants. Surface & Coatings Technology 403 (2020) 126381. doi: /

  18. H. Martin-Gómez, L. Oliver-Cervelló, J. Buxadera-Palomero, M.P. Ginebra, C. Mas-Moruno. Chemically Diverse Multifunctional Peptide Platforms with Antimicrobial and Cell Adhesive Properties. ChemBioChem 2020, 21, 1–7. doi:

  19. J. Buxadera-Palomero, K. Albó, F.J. Gil, C. Mas-Moruno, D. Rodríguez. Polyethylene Glycol Pulsed Electrodeposition for the Development of Antifouling Coatings on Titanium. Coatings 2020, 10(5), 456; doi:

  20. R. Padrós, M. Punset, M. Molmeneu, A. Brizuela-Velasco, M. Herrero-Climent, E. Rupérez, F.J. Gil. Mechanical Properties of CoCr Dental-Prosthesis Restorations made by Three Manufacturing Processes. Influence of the Microstructure and Topography. Metals 2020, 10, 788. doi:10.3390/met10060788.

  21. R. Padrós, L. Giner-Tarrida, M. Herrero-Climent, M. Punset, F.J. Gil. Corrosion Resistance and Ion Release of Dental Prosthesis of CoCr Obtained by CAD-CAM Milling, Casting and Laser Sintering. Metals 2020, 10, 827; doi:10.3390/met10060827.

  22. J. Franch, A. Barba, K. Rappe, Y. Maazouz, M.P Ginebra. Use of three-dimensionally printed β-tricalcium phosphate synthetic bone graft combined with recombinant human bone morphogenic protein-2 to treat a severe radial atrophic nonunion in a Yorkshire terrier. Veterinary Surgery. 2020;1–6. doi: 10.1111/vsu.13476.



  1. J. Guillem-Marti, M. Gelabert, A. Heras-Parets, M. Pegueroles,M.P Ginebra, J.M. Manero. RGD Mutation of the Heparin Binding II Fragment of Fibronectin for Guiding Mesenchymal Stem Cell Behavior on Titanium Surfaces. ACS Appl. Mater. Interfaces 2019, 11, 3666−3678. doi: 10.1021/acsami.8b17138

  2. M. Godoy-Gallardo, C. Labay, L. Hosta-Rigau. Tyrosinase-Loaded Multicompartment Microreactor toward Melanoma Depletion. ACS Appl. Mater. Interfaces, 2019, 11 (6), pp 5862–5876. doi: 10.1021/acsami.8b20275

  3. A. Barba, A. Diez-Escudero, M. Espanol, M. Bonany, J.M. Sadowska, J. Guillem-Marti, C. Öhman-Mägi, C. Persson, M.C. Manzanares, J. Franch, M.P. Ginebra. The impact of biomimicry in the design of osteoinductive bone substitutes: nanoscale matters. ACS ACS Appl. Mater. Interfaces 2019, 11, 8818−8830. doi: 10.1021/acsami.8b20749.

  4. J.M. Sadowska, F. Wei, J. Guo, J. Guillem-Marti, Z. Lin, M.-P. Ginebra, Yin Xiao. The effect of biomimetic calcium deficient hydroxyapatite and sintered β-tricalcium phosphate on osteoimmune reaction and osteogenesis. Acta Biomaterialia 96 (2019) 605–618. doi:

  5. R. Fraioli, S. Neubauer, F. Rechenmacher, B.M. Bosch, K. Dashnyam, J.H. Kim, R. A. Perez, H.W. Kim, F.J. Gil, M.P. Ginebra, J.M. Manero, H. Kessler, C. Mas-Moruno. Control of stem cell response and bone growth on biomaterials by fully non-peptidic integrin selective ligands. Biomater. Sci., 2019,7, 1281-1285. doi: 10.1039/c8bm01466c.

  6. M. Fernández-Arias, M. Boutinguiza, J. del Val, E. Medina, D. Rodríguez, A. Riveiro, R. Comesaña, F. Lusquiños, F.J. Gil, J. Pou. RE-irradiation of silver nanoparticles obtained by laser ablation in water and assessment of their antibacterial effect. Applied Surface Science 473 (2019) 548–554. . doi:

  7. M. Fernández-Yagüe, R. Perez-Antoñanzas, J.J. Roa, M. Biggs, F.J. Gil, M. Pegueroles. Enhanced osteoconductivity on electrically charged titanium implants treated by physicochemical surface modifications methods. Nanomedicine: Nanotechnology, Biology, and Medicine 18 (2019) 1– 10. doi: 

  8. M. Hoyos-Nogués, E. Falgueras-Batlle, M.P. Ginebra, J.M. Manero, J. Gil, C. Mas-Moruno. A Dual Molecular Biointerface Combining RGD and KRSR Sequences Improves Osteoblastic Functions by Synergizing Integrin and Cell-Membrane Proteoglycan Binding. Int. J. Mol. Sci. 2019, 20, 1429; doi:10.3390/ijms20061429.

  9. L. Vojtova, L. Michlovska, K. Valova, M. Zboncak, M. Trunec, K. Castkova, M. Krticka, V. Pavlinakova, P. Polacek, M. Dzurov, V. Lukasova, M. Rampichova, T. Suchy, R. Sedlacek, M.P. Ginebra, E.B. Montufar. The Effect of the Thermosensitive Biodegradable PLGA⁻PEG⁻PLGA Copolymer on the Rheological, Structural and Mechanical Properties of Thixotropic Self-Hardening Tricalcium Phosphate Cement.. Int J Mol Sci. 2019 Jan 17;20(2). pii: E391.doi: 10.3390/ijms20020391.

  10. J. Tornin, M. Mateu-Sanz, A. Rodríguez, C. Labay, R. Rodríguez, C. Canal. Pyruvate Plays a Main Role in the Antitumoral Selectivity of Cold Atmospheric Plasma in Osteosarcoma. Scientific Reportsvolume 9, Article number: 10681 (2019). doi: 

  11. A. Rodríguez-Contreras, J.i Guillem-Marti, O. Lopez, J.M. Manero, E. Ruperez. Antimicrobial PHAs coatings for solid and porous tantalum implants. Colloids and Surfaces B: Biointerfaces 182 (2019) 110317. doi:

  12. G. Boix-Lemonche, J. Guillem-Marti, F. D'Este, J.M. Manero, B. Skerlavaj. Covalent grafting of titanium with a cathelicidin peptide produces an osteoblast compatible surface with antistaphylococcal activity. Colloids and Surfaces B: Biointerfaces 185 (2020) 110586. doi:

  13. J. Guillem-Marti, N. Cinca, M. Punset, I. García Cano, F.J. Gil, J.M. Guilemany, S Dost. Porous titanium-hydroxyapatite composite coating obtained on titanium by cold gas spray with high bond strength for biomedical applications. Colloids and Surfaces B: Biointerfaces 180 (2019) 245–253. doi:

  14. C. Labay, I. Hamouda, F. Tampieri, M.P. Ginebra, C. Canal. Production of reactive species in alginate hydrogels for cold atmospheric plasma-based therapies. Scientific Reports, 9, 16160 (2019). doi:

  15. J.A. Picas, M. Punset, E. Rupérez, S. Menargues, E. Martin, M.T. Baile. Corrosion mechanism of HVOF thermal sprayed WC-CoCr coatings in acidic chloride media. Surface & Coatings Technology 371 (2019) 378–388. doi: ISNN: 0257-8972.

  16. A. Khlyustova, C. Labay, Z. Machala, M.P. Ginebra, C.Canal. Important parameters in plasma jets for the production of RONS in liquids for plasma medicine: a brief review. Frontiers of Chemical Science and Engineering. Doi:

  17. E. Vidal, J. Buxadera-Palomero, C. Pierre, J.M. Manero, M.P. Ginebra, S. Cazalbou, C. Combes, E. Rupérez, D. Rodriguez. Single-step pulsed electrodeposition of calcium phosphate coatings on titanium for drug delivery. Surface & Coatings Technology 358 (2019) 266–275. doi: 10.1016/j.surfcoat.2018.11.037. 

  18. A. Przekora, J. Pawlat, P. Terebun, D. Duday, C. Canal, S. Hermans, M. Audemar, C. Labay, J.-S. Thomann, G. Ginalska. The effect of low temperature atmospheric nitrogen plasma on MC3T3-E1 preosteoblast proliferation and differentiation in vitro. Journal of Physics D: Applied Physics (2019) 52: 275401. doi: 

  19. A. Diez‐Escudero, E. Torreggiani, G. Di Pompo, M. Espanol, C. Persson, G. Ciapetti, N. Baldini, M. Ginebra, Effect of calcium phosphate heparinization on the in vitro inflammatory response and osteoclastogenesis of human blood precursor cells, J. Tissue Eng. Regen. Med. 13 (2019) term.2872. doi:// 

  20. U. Cvelbar, J.L. Walsh, M. Černák, H.W. de Vries, S. Reuter, Th. Belmonte, C. Corbella, C. Miron, N. Hojnik, A. Jurov, H. Puliyalil, M. Gorjanc, S. Portal, R. Laurita, V. Colombo, J. Schäfer, A. Nikiforov, M. Modic, O. Kylian, M. Polak, C. Labay, J.M. Canal, C. Canal, M. Gherardi, K. Bazaka, P. Sonar, K.K. Ostrikov, D. Cameron, S. Thomas, K.D. Weltmann. White paper on the future of plasma science and technology in plastics and textiles. Plasma Process Polym.2019;16:e1700228. doi: 10.1002/ppap.201700228

  21. A. Brizuela, M. Herrero-Climent, E. Rios-Carrasco, J.V. Rios-Santos, R.A. Pérez, J.M. Manero, J. Gil Mur. Influence of the Elastic Modulus on the Osseointegration of Dental Implants. Materials 2019, 12, 980; doi:10.3390/ma12060980.

  22. A. Cirera , M.C. Manzanares , P. Sevilla, M. Ortiz-Hernandez, P. Galindo-Moreno, J. Gil. Biofunctionalization with a TGF-1 Inhibitor Peptide in the Osseointegration of Synthetic Bone Grafts: An In Vivo Study in Beagle Dogs. Materials 2019, 12, 3168; doi:10.3390/ma12193168.

  23. E. Velasco-Ortega, A. Flichy-Fernández, M. Punset, A. Jiménez-Guerra, J.M. Manero, J. Gil. Fracture and Fatigue of Titanium Narrow Dental Implants: New Trends in Order to Improve the Mechanical Response. Materials 2019, 12, 3728; doi: 10.3390/ma12223728.

  24. A. Hoornaert, Y. Maazouz, D. Pastorino, C. Aparicio, G. de Pinieux, B. H. Fellah, M.-P. Ginebra, P. Layrolle. Vertical bone regeneration with synthetic biomimetic calcium phosphate onto the calvaria of rats. Tissue Eng Part C Methods. 2019 Jan;25(1):1-11. doi: 10.1089/ten.TEC.2018.0260.

  25. E. Dávila, M. Ortiz-Hernández, R.A. Perez, M. Herrero-Climent, M. Cerrolaza, F.J. Gil. Crestal module design optimization of dental implants: finite element analysis and in vivo studies. Journal of Materials Science: Materials in Medicine (2019) 30:90. doi:



  1. J. M. Sadowska, F. Wei, J. Guo, J. Guillem-Marti, M.P. Ginebra, Y. Xiao. Effect of nano-structural properties of biomimetic hydroxyapatite on osteoimmunomodulation. Biomaterials 181 (2018) 318–332. doi:

  2. J.M. Sadowska, J. Guillem-Marti, M. Espanol, Ch. Stähli, N. Döbelin, M.P. Ginebra. In vitro response of mesenchymal stem cells to biomimetic hydroxyapatite substrates: A new strategy to assess the effect of ion exchange. Acta Biomaterialia 76 (2018) 319–332. doi: 10.1016/j.actbio.2018.06.025.

  3. A. Barba, Y. Maazouz, A. Diez-Escudero, K. Rappe, M. Espanol, E.B. Montufar, C. Öhman-Mägi, C. Persson, P. Fontecha, M.C. Manzanares, J. Franch, M.P. Ginebra. Osteogenesis by foamed and 3D-printed nanostructured calcium phosphate scaffolds: Effect of pore architecture. Acta Biomaterialia 79 (2018) 135–147. doi:

  4. S. Raymond, Y. Maazouz, E.B. Montufar, R.A. Perez, B. González, J. Konka, J. Kaiser, M.P. Ginebra. Accelerated hardening of nanotextured 3D-plotted self-setting calcium phosphate inks. Acta Biomaterialia 75 (2018) 451–462.

  5. A. Diez-Escudero, M. Espanol, X. Lu, C. Persson, M.-P. Ginebra. Heparinization of Beta Tricalcium Phosphate: Osteoimmunomodulatory Effects. Adv Healthc Mater. 2018 Mar;7(5). doi: 10.1002/adhm.201700867. 

  6. C. Mas-Moruno, B. Su, M.J. Dalby. Multifunctional Coatings and Nanotopographies: Toward Cell Instructive and Antibacterial Implants. Adv. Healthcare Mater. 2018, 1801103. doi: 10.1002/adhm.201801103.

  7. J.M. Sadowska, J. Guillem-Marti, M.-P. Ginebra. The influence of physicochemical properties of biomimetic hydroxyapatite on the in vitro behavior of endothelial progenitor cells and their interaction with mesenchymal stem cells. Adv. Healthcare Mater. 2018, 1801138. doi: 10.1002/adhm.201801138.

  8. G. Mestres, M.A. Fernandez-Yague, D. Pastorino, E.B. Montufar, C. Canal, M.C. Manzanares-Céspedes, M.P. Ginebra. In vivo efficiency of antimicrobial inorganic bone grafts in osteomyelitis treatments. Materials Science & Engineering C 97 (2019) 84–95. doi: ISSN: 0928-4931. Impact Factor: 5.080. Q1 6/33 Materials Science, Biomaterials. 

  9. J. Guillem-Marti, G. Boix-Lemonche, D. Gugutkov, M.P. Ginebra, G. Altankov, J.M. Manero. Recombinant fibronectin fragment III8-10/polylactic acid hybrid nanofibers enhance the bioactivity of titanium surface. Nanomedicine (Lond). 2018 Apr;13(8):899-912. Epub 2018 Mar 22. doi: 10.2217/nnm-2017-0342

  10. Y. Qi, Zh. Ye, Al. Fok, B.N. Holmes, M. Espanol, M.P. Ginebra, C. Aparicio. Effects of Molecular Weight and Concentration of Poly(Acrylic Acid) on Biomimetic Mineralization of Collagen. ACS Biomater. Sci. Eng., 2018, 4 (8), pp 2758–2766. DOI: 10.1021/acsbiomaterials.8b00512.

  11. M. Ortiz-Hernandez, K. S. Rappe, M. Molmeneu, C. Mas-Moruno, J. Guillem-Martí, M. Punset, C. Caparros, J. Calero, J. Franch, M. Fernandez-Fairen, J. Gil. Two Different Strategies to Enhance Osseointegration in Porous Titanium: Inorganic Thermo-Chemical Treatment Versus Organic Coating by Peptide Adsorption. Int. J. Mol. Sci. 2018, 19(9), 2574; doi:

  12. M. Hoyos-Nogués, J. Buxadera-Palomero, M.-P. Ginebra, J.M. Manero, F.X. Gil, C. Mas-Moruno. All-in-one trifunctional strategy: A cell adhesive, bacteriostatic and bactericidal coating for titanium implants. Colloids and Surfaces B: Biointerfaces 169 (2018) 30–40. doi: 10.1016/j.colsurfb.2018.04.050

  13. K. Khurana, F. Müller, K. Jacobs, Th. Faidt, J-U. Neurohr, S. Grandthyll, F. Mücklich, C. Canal, M.P. Ginebra. Plasma polymerized bioceramics for drug delivery: Do surface changes alter biological behaviour? European Polymer Journal 107 (2018) 25–33. doi:

  14. G. Scionti, L. Rodriguez-Arco, M.T. Lopez-Lopez, A.L. Medina-Castillo, I. Garzón, M. Alaminos, M. Toledano, R. Osorio. Effect of functionalized PHEMA micro- and nano-particles on the viscoelastic properties of fibrin-agarose biomaterials. J Biomed Mater Res A. 2018 Mar;106(3):738-745. doi: 10.1002/jbm.a.36275

  15. E. Vidal, J. Buxadera-Palomero, C. Pierre, J.M. Manero, M.P. Ginebra, S. Cazalbou, C. Combes, E. Rupérez, D. Rodriguez. Single-step pulsed electrodeposition of calcium phosphate coatings on titanium for drug delivery. Surface & Coatings Technology 358 (2019) 266–275. doi: 10.1016/j.surfcoat.2018.11.037.

  16. J.A. Picas, M. Punset, E. Rupérez de Gracia, S. Menargues, E. Martin, M.T. Baile Puig. Corrosion mechanism of HVOF thermal sprayed WC-CoCr coatings in acidic chloride media. Surface and coatings technology (2018). doi: . ISNN: 0257-8972. Impact Factor: 2.906. Q1 4/19 Materials Science, Coatings and Films

  17. C. Lo Porto, F. Palumbo, J. Buxadera-Palomero, C, Canal, P. Jelinek, L. Zajickova, P. Favia. On the plasma deposition of vancomycin-containing nano-capsules for drug-delivery applications. Plasma Process Polym. 2018;e1700232. doi:

  18. M. Hoyos-Nogués, F. J. Gil, C. Mas-Moruno. Antimicrobial Peptides: Powerful Biorecognition Elements to Detect Bacteria in Biosensing Technologies. Molecules 2018, 23, 1683; doi:10.3390/molecules23071683.

  19. A. Brizuela-Velasco, E. Pérez-Pevida, A. Jiménez-Garrudo, F.J. Gil-Mur, J.M. Manero, M. Punset-Fuste, D. Chávarri-Prado, M. Diéguez-Pereira6, F. Monticelli. Mechanical Characterisation and Biomechanical and Biological Behaviours of Ti-Zr Binary-Alloy Dental Implants. BioMed Research International, Volume 2017, Article ID 2785863, 10 pages. doi:

  20. M. Boutinguiza, M. Fernández-Arias, J. del Val, J. Buxadera-Palomero, D. Rodríguez, F. Lusquiños, F.J. Gil, J. Pou. Synthesis and deposition of silver nanoparticles on cp Ti by laser ablation in open air for antibacterial effect in dental implants. Materials Letters 231 (2018) 126–129. doi:

  21. F. Gil, E. Rupérez de Gracia, E. Velasco, C. Aparicio, J. M. Manero. Mechanism of fracture of NiTi superelastic endodontic rotary instruments. Journal of materials science. Materials in medicine. (2018) Volume 29 Issue 131. doi: ISSN: 0957-4530. Factor: 2.448. Q2 29/78 Engineering, Biomedical.

  22. L. Giner, M. Mercade, S. Torrent, M. Punset, R. Pérez-Antoñanzas, L. Delgado, F.J. Gil. Double acid etching treatment of dental implants for enhanced biological properties. J Appl Biomater Funct Mater. 2018 Apr;16(2):83-89. doi: 10.5301/jabfm.5000376. ISSN: 2280-8000. Impact Factor: 1.397. Q3 55/78 Engineering, Biomedical.

  23. J. Vilarrasa, L. Delgado, M. Galofré, J.M. Manero, In vitro evaluation of a multispecies oral biofilm over antibacterial coated titanium surfaces. J Mater Sci Mater Med. 2018 Nov 3;29(11):164. doi: 10.1007/s10856-018-6168-8. ISSN: 0957-4530. Factor: 2.448. Q2 29/78 Engineering, Biomedical.



  1. A. Barba, A. Diez-Escudero, Y. Maazouz, K. Rappe, M. Espanol, E.B. Montufar, M. Bonany, J.M. Sadowska, J: Guillem-Marti, C. Öhman-Mägi, C. Persson, M.C. Manzanares, J. Franch, M.P. Ginebra. Osteoinduction by Foamed and 3D-Printed Calcium Phosphate Scaffolds: Effect of Nanostructure and Pore Architecture. ACS Appl Mater Interfaces. 2017 Nov 20. doi: 10.1021/acsami.7b14175

  2. M. Hoyos-Nogués, F. Velasco, M.-P. Ginebra, J.M. Manero, F.X. Gil and C. Mas-Moruno. Regenerating bone via multifunctional coatings: the blending of cell integration and bacterial inhibition properties on the surface of biomaterials. ACS Appl Mater Interfaces. 2017 Jul 5;9(26):21618-21630. doi: 10.1021/acsami.7b03127.

  3. Y. Maazouz, E.B. Montufar, J. Malbert, M. Espanol, M.P.Ginebra. Self-hardening and thermoresponsive alpha tricalcium phosphate/pluronic pastes. Acta Biomaterialia 49 (2017) 563-574. doi:

  4. A. Diez-Escudero, M. Espanol, S. Beats, M.P. Ginebra. In vitro degradation of calcium phosphates: effect of multiscale porosity, textural properties and composition. Acta Biomaterialia 60 (2017):81-92. doi:

  5. R. O'Neill, H.O. McCarthy, E. Montufar, M.P. Ginebra, D.I. Wilson, A. Lennon, N. Dunne. Critical Review: Injectability of Calcium Phosphate Pastes and Cements. Acta Biomaterialia 50, 1 March 2017, Pages 1–19. doi:

  6. G. Ciapetti, G. di Pompo, A. Diez-Escudero, E.B. Montufar, M.P. Ginebra S. Avnet, D. Martini, N. Baldini. Osteoclast differentiation from human blood precursors on biomimetic calcium-phosphate substrates. Acta Biomaterialia 50, 1 March 2017, Pages 102–113. doi:

  7. C. Canal, R. Fontelo, I. Hamouda, J. Guillem-Martí, U. Cvelbar, M.P. Ginebra. Plasma-induced selectivity in bone cancer cells death. Free Radical Biology and Medicine 110 (2017) 72-80. doi:

  8. T.G. Kapp, F. Rechenmacher, S. Neubauer, O.V. Maltsev, E.A. Cavalcanti-Adam, R. Zarka, U. Reuning, J. Notni, H-J Wester, C. Mas-Moruno, J. Spatz, B. Geiger, H. Kessler. A Comprehensive Evaluation of the Activity and Selectivity Profile of Ligands for RGD-binding Integrins. Scientific Reports 7, Article number: 39805 (2017). doi:10.1038/srep39805

  9. R. Schieber, F. Lasserre, M. Hans, M. Fernández-Yagüe, M. Díaz-Ricart, G. Escolar, M.P. Ginebra, F. Mücklich, M. Pegueroles. Controlled endothelial cell and platelet adhesion onto patterned CoCr alloy surfaces by Direct Laser Interference Patterning technique for cardiovascular applications. Adv Healthc Mater. 2017 Jul 17. doi: 10.1002/adhm.201700327.

  10. A. Diez-Escudero, M. Espanol, X. Lu, C. Persson, M.-P. Ginebra. Heparinization of Beta Tricalcium Phosphate: Osteoimmunomodulatory Effects. Advanced Healthcare Materials, accepted November 2017.

  11. R. Fraioli, P.M. Tsimbouri, L.E. Fisher, A.H. Nobbs, B. Su, S. Neubauer, F. Rechenmacher, H. Kessler, M.P. Ginebra, M.J. Dalby, J.M. Manero, C Mas-Moruno. Towards the cell-instructive bactericidal substrate: exploring the combination of nanotopographical features and integrin selective synthetic ligands. Scientific Reports 7, Article number: 16363 (2017). doi:10.1038/s41598-017-16385-3.

  12. M. Motisuke, G. Mestres, C. O. Renó, R.G. Carrodeguas, C.A.C. Zavaglia, M.P. Ginebra. Influence of Si substitution on the reactivity of α-Tricalcium Phosphate. Materials Science and Engineering C, Volume 75, 1 June 2017, Pages 816-821. doi:

  13. J. Buxadera-Palomero, C. Calvo, S. Torrent-Camarero, F.J. Gil, C. Mas-Moruno, C. Canal, D. Rodríguez. Biofunctional polyethylene glycol coatings on titanium: An in vitro-based comparison of functionalization methods. Colloids Surf B Biointerfaces. 2017 Jan 24;152:367-375. doi: 10.1016/j.colsurfb.2017.01.042.

  14. A. Diez-Escudero, M. Espanol, E.B. Montufar, G. Di Pompo, G. Ciapetti, N. Baldini, M.P. Ginebra. Focus ion beam / Scanning electron microscopy characterisation of osteoclastic resorption of calcium phosphate substrates. Tissue Eng Part C Methods. 2017 Feb;23(2):118-124. doi: 10.1089/ten.TEC.2016.0361.

  15. J.M. Sadowska, J. Guillem-Marti, E.B. Montufar, M. Espanol, M.P. Ginebra. Biomimetic versus Sintered Calcium Phosphates: The in vitro Behavior of Osteoblasts and Mesenchymal Stem Cells. Tissue Eng Part A. 2017 Jan 20. doi: 10.1089/ten.TEA.2016.0406.

  16. A. Rodríguez-Contreras, Y. García, J.M. Manero, E. Rupérez. Antibacterial PHAs coating for titanium implants. European Polymer Journal. Volume 90, May 2017, Pages 66–78. doi:

  17. M.I. Castellanos, J. Guillem-Marti, C. Mas-Moruno, M. Díaz-Ricart, G. Escolar, M.P. Ginebra, F.J. Gil, M. Pegueroles, J.M. Manero. Cell adhesive peptides functionalized on CoCr alloy stimulate endothelialization and prevent thrombogenesis and restenosis. J Biomed Mater Res Part A 2017:00A:000–000. doi: 10.1002/jbm.a.35988.

  18. M.I. Castellanos, C. Mas-Moruno, A. Graua, X. Serra-Picamal, X. Trepat, F. Albericio, M. Joner, F.J. Gil, M.P. Ginebra, J.M. Manero, M. Pegueroles. Functionalization of CoCr surfaces with cell adhesive peptides to promote HUVECs adhesion and proliferation. Applied Surface Science 393 (2017) 82–92. doi:

  19. I. Ajaxon, A. Acciaioli, G. Lionello, M.P. Ginebra, C. Öhman-Mägi, M. Baleani, C. Persson. Elastic properties and strain-to-crack-initiation of calcium phosphate bone cements: revelations of a high-resolution measurement technique. J Mech Behav Biomed Mater. 2017 Oct;74:428-437. doi: 10.1016/j.jmbbm.2017.06.023.

  20. S. Gallinetti, G. Mestres, C. Canal, C. Persson, M.P. Ginebra. A novel strategy to enhance interfacial adhesion in fiber-reinforced calcium phosphate cement. Journal of Mechanical Behaviour of Biomedical Materials 75 (2017) :495-503. doi: 10.1016/j.jmbbm.2017.08.017.

  21. U. Cvelbar, C. Canal, M. Hori. Editorial: Plasma-inspired biomaterials. J. Phys. D: Appl. Phys. 50 (2017) 040201 (4pp) doi:10.1088/1361-6463/50/4/040201.

  22. E. Gilabert-Chirivella, R. Perez, C. Ribeiro, S. Ribeiro, D.M. Correia, M.L. Gonzalez-Martin, J.M. Manero, S. Lanceros-Mendez, G. Gallego, J. Gómez. Chitosan patterning on titanium implants. Progress in Organic Coatings. Volume 111, October 2017, Pages 23–28. doi:

  23. S. Lewin, A. Barba, C. Persson, J. Franch, M.P. Ginebra, C. Öhman-Mägi. Evaluation of bone formation in calcium phosphate scaffolds with μCT-method validation using SEM. Biomed. Mater. 12 (2017) 065005. doi:

  24. M. Herrero-Climent, M.M. Romero Ruiz, P. Lázaro Calvo, J.V. Ríos Santos, R.A. Perez, F.J Gil Mur. Effectiveness of a new dental implant bioactive surface: histological and histomorphometric comparative study in minipigs. Clin Oral Investig. 2017 Oct 12. doi: ISSN: 1432-6981. Impact Factor: 2.207. Q1 21/89 Dentistry, Oral Surgery & Medicine.

  25. E. Velasco, L Monsalve-Guil, A. Jimenez, I. Ortiz, J.Moreno-Muñoz, E. Nuñez-Marquez, M. Pegueroles, R A. Pérez, F.J. Gil. Importance of the Roughness and Residual Stresses of Dental Implants on Fatigue and Osseointegration Behavior. In Vivo Study in Rabbits. Journal of Oral Implantology, Vol. XLII /No. Six /2016. doi: 10.1563/aaid-joi-D-16-00088.

  26. P.Sevilla, J.Gil, C.Aparicio. Relevant Properties for Immobilizing Short Peptides on Biosurfaces. IRBM 38(2017)256–265. doi: ISSN: 1959-0318.  



  1. C. Mas-Moruno, R. Fraioli, F. Rechenmacher, S. Neubauer, T. G. Kapp, H. Kessler. avb3- or a5b1-Integrin-Selective Peptidomimetics for Surface Coating. Angew. Chem. Int. Ed. 2016, 55, 7048 – 7067. doi: 10.1002/anie.201509782

  2. Z. Zhao, M. Espanol, J. Guillem-Marti, D. Kempf, A. Diez-Escudero, M.P. Ginebra. Ion-doping as a strategy to modulate hydroxyapatite nanoparticle internalization. Nanoscale, 2016, 8, 1595. doi: 10.1039/c5nr05262a

  3. M. Hoyos-Nogués, S. Brosel-Oliu, N. Abramova, F.X. Muñoz, A.Bratov, C. Mas-Moruno, F.J. Gil. Impedimetric antimicrobia lpeptide-based sensor for the early detection of periodontopathogenic bacteria. Biosensors and Bioelectronics86(2016)377–385. doi:

  4. M. Espanol, G. Mestres, Th. Luxbacher, J.B. Dory, M.P Ginebra. Impact of Porosity and Electrolyte Composition on the Surface Charge of Hydroxyapatite Biomaterials. ACS Appl. Mater. Interfaces, 2016, 8 (1), pp 908–917. doi: 10.1021/acsami.5b10404

  5. C. Herranz-Diez, C. Mas-Moruno, S. Neubauer, H. Kessler, F.J. Gil, M. Pegueroles, J.M. Manero, J. Guillem-Marti. Tuning mesenchymal stem cell response onto titanium-niobium-hafnium alloy by recombinant fibronectin fragments. ACS Appl. Mater. Interfaces, 2016, 8 (4), pp 2517-2525. doi: 10.1021/acsami.5b09576

  6. R. Fraioli, K. Dashnyam, J.H. Kim, R.A. Perez, H.W. Kim, J. Gil, M.P. Ginebra, J.M. Manero, C. Mas-Moruno. Surface guidance of stem cell behavior: Chemically tailored co-presentation of integrin-binding peptides stimulates osteogenic differentiation in vitro and bone formation in vivo. Acta Biomaterialia 43 (2016) 269–281. doi:

  7. H. Aubin, C. Mas-Moruno, M. Iijima, N. Schütterle, M. Steinbrink, Assmann, F.J. Gil, A. Lichtenberg, M. Pegueroles, P. Akhyari. Customized Interface Biofunctionalization of Decellularized Extracellular Matrix: Toward Enhanced Endothelialization. Tissue Engineering: Part C, Volume 22, Number 5, 2016. DOI: 10.1089/ten.tec.2015.0556

  8. C. Canal, M. Modic, U. Cvelbarc, M.P. Ginebra. Regulating the antibiotic drug release from β-tricalcium phosphate ceramics by atmospheric plasma surface engineering. Biomater. Sci., 2016, 4, 1454. doi: 10.1039/c6bm00411c

  9. C. Canal, K. Khurana, S. Gallinetti, S. Bhatt, J. Pulpytel, F Arefi-Khonsari, M.P. Ginebra. Design of Calcium Phosphate Scaffolds with controlled Simvastatin release by Plasma polymerization. Polymer, v.92, 2016, pp.170-178. doi: 10.1016/j.polymer. 2016.03.069

  10. Maria Godoy-Gallardo, Jordi Guillem-Marti, Pablo Sevilla, José M. Manero, Francisco J. Gil, Daniel Rodriguez. Anhydride-functional silane immobilized onto titaniumsurfaces induces osteoblast cell differentiation and reduces bacterial adhesion and biofilm formation. Materials Science and Engineering C 59 (2016) 524-532.

  11. G. Mestres, K. Kugiejko, D. Pastorino, J.Unosson, C. Öhman, M. Karlsson Ott, M.-P. Ginebra, C. Persson. Changes in the drug release pattern of fresh and set simvastatin-loaded. Materials Science and Engineering C 58(2016) 88-96.

  12. Godoy-Gallardo M., Manzanares-Céspedes M.C., Sevilla P., Nart J., Manzanares N., Manero J.M., Gil F.J., Boyd S.K., Rodríguez D., Evaluation of bone loss in antibacterial coated dental implants: An experimental study in dogs. Materials Science and Engineering C 69 (2016) 538–545. doi:10.1016/j.msec.2016.07.020.

  13. J. Luo, I. Ajaxon, M.P. Ginebra, H. Engqvist, C. Persson. Compressive, diametral tensile and biaxial flexural strength of cutting-edge calcium phosphate cements. Journal of the Mechanical Behavior of Biomedical Materials 60(2016) 617-27. doi: 

  14. M. Hamed Misbah, M. Espanol, L. Quintanilla, M.P. Ginebra, J.C. Rodríguez-Cabello. Formation of calcium phosphate nanostructures under the influence of self-assembling hybrid elastin-like-statherin recombinamers. RSC Adv., 2016, 6, 31225-31234. doi: 10.1039/x0xx00000x.

  15. Sevilla, P.; Vining, K.; Dotor, J.; Rodriguez, D.; Gil, F.J.; Aparicio, C.. Surface immobilization and bioactivity of TGF-ß1 inhibitor peptides for bone implant applications. Journal of biomedical materials research. Part B, Applied biomaterials. Volume 104, Issue 2, 1 February 2016, Pages 385-394. doi: 10.1002/jbm.b.33374. 

  16. J. Unosson, E. B. Montufar, H. Engqvist, M.P. Ginebra, C. Persson. Brushite foams - the effect of Tween® 80 and Pluronic® F-127 on foam porosity and mechanical properties. J Biomed Mater Res B Appl Biomater. 2016 Jan;104(1):67-77. doi: 10.1002/jbm.b.33355

  17. C. Labay, J. Buxadera-Palomero, M. Avilés, C. Canal, M.P. Ginebra. Modulation of release kinetics by plasma polymerization of ampicillin-loaded β-TCP ceramics. J. Phys. D: Appl. Phys. 49 (2016) 304004 (10pp). doi:10.1088/0022-3727/49/30/304004

  18. E. Rupérez, J.M. Manero, L.A. Bravo-González, E. Espinar, F.J. Gil. Development of Biomimetic NiTi Alloy: Influence of Thermo-Chemical Treatment on the Physical, Mechanical and Biological Behavior. Materials 2016, 9, 402. doi:10.3390/ma9060402

  19. A. Rodríguez-Contreras, M. S. Marqués-Calvo, F.J. Gil, J.M. Manero. Modification of titanium surfaces by adding antibiotic-loaded PHB spheres and PEG for biomedical applications. J Mater Sci: Mater Med (2016) 27:124. doi: 10.1007/s10856-016-5723-4.

  20. C. Caparrós, M. Ortiz-Hernandez, M. Molmeneu, M. Punset, J.A. Calero, C. Aparicio, M. Fernández-Fairén, R. Perez, F.J. Gil. Bioactive macroporous titanium implants highly interconnected. J Mater Sci: Mater Med (2016) 27:151. doi: 10.1007/s10856-016-5764-8.

  21. R. O'Neill, E. B. Montufar, M.P. Ginebra, I. Wilson, A. Lennon, N. Dunne. Extent and Mechanism of Phase Separation during the Extrusion of Calcium Phosphate Pastes. Journal of Materials Science. Materials in Medicine, 2016 Feb;27(2):29. doi: 10.1007/s10856-015-5615-z

  22. E. Espinar-Escalona, L.A. Bravo-Gonzalez, M. Pegueroles, F.J. Gil. Roughness and wettability effect on histological and mechanical response of self-drilling orthodontic mini-implants. Clin Oral Invest (2016) 20:1115–1120. doi: 10.1007/s00784-016-1770-y



  1. C. Labay, J.M. Canal, M. Modic, U. Cvelbar, M. Quiles, M. Armengol, M.A. Arbos, F.J. Gil, C. Canal. Antibiotic-loaded polypropylene surgical meshes with suitable biological behaviour by plasma functionalization and polymerization. Biomaterials 71 (2015) 132- doi: 10.1016/j.biomaterials.2015.08.023.144

  2. N. Marín-Pareja, M. Cantini, C. González-García, E. Salvagni, M. Salmerón-Sánchez, M.P. Ginebra. Different Organization of Type I Collagen Immobilized on Silanized and Nonsilanized Titanium Surfaces Affects Fibroblast Adhesion and Fibronectin Secretion. ACS Appl. Mater. Interfaces, 2015, 7 (37), pp 20667-20677. doi 10.1021/acsami.5b05420. ISSN 1944-8244. Impact Factor: 7.145. Q1 25/271 Materials Science, Multidisciplinary; Q1 14/83 Nanoscience & Nanotechnology.

  3. M. Godoy-Gallardo, Zh. Wang, Y. Shen, J.M. Manero, F.J. Gil, D. Rodriguez, M. Haapasalo. Antibacterial Coatings on Titanium Surfaces: A Comparison Study Between in Vitro Single-Species and Multispecies Biofilm. ACS Appl. Mater. Interfaces 2015, 7, 5992?6001. doi: 10.1021/acsami.5b00402

  4. D. Pastorino, C. Canal, M.P. Ginebra. Multiple characterization study on porosity and pore structure of calcium phosphate cements. Acta Biomaterialia (2015) 205-214, doi: 10.1016/j.actbio.2015.09.017

  5. D. Pastorino, C. Canal, M.P. Ginebra. Drug delivery from injectable calcium phosphate foams by tailoring the macroporosity-drug interaction. Acta Biomaterialia 12 (2015):250-9. doi: 10.1016/j.actbio.2014.10.031

  6. Kovtun, M.J. Goeckelmann, A.A. Niclas, E.B. Montufar, M.P. Ginebra, J.A. Planell, M. Santin, A. Ignatius. In vivo performance of novel soybean/gelatin-based bioactive and injectable hydroxyapatite foams. Acta Biomater. 12 (2015): 242-249. doi: 10.1016/j.actbio.2014.10.034

  7. E. Unosson, D. Rodriguez, K. Welch, H. Engqvist. Reactive combinatorial synthesis and characterization of a gradient Ag-Ti oxide thin film with antibacterial properties. Acta Biomater 2015 Jan 1;11:503-10. doi: 10.1016/j.actbio.2014.09.048

  8. P. Rocas, M. Hoyos-Nogués, J. Rocas, J.M. Manero, J. Gil, F. Albericio, C. Mas-Moruno. Installing multifunctionality on titanium with RGD-decorated polyurethane-polyurea roxithromycin loaded nanoparticles: toward new osseointegrative therapies. Adv Healthc Mater. 2015 Sep 16;4(13):1956-60. doi: 10.1002/adhm.201500245

  9. Godoy-Gallardo, M., Mas-Moruno, C., Yu, K., Manero, J.M., Gil, F.J., Kizhakkedathu, J., Rodriguez, D. Antibacterial Properties of hLf1-11 Peptide onto Titanium Surfaces: A Comparison Study Between Silanization and Surface Initiated Polymerization. Biomacromolecules. 16 (2015):483-96. doi: 10.1021/bm501528x

  10. E. Rupérez, J.M. Manero, K. Riccardi, Yuping Li, C. Aparicio, F.J. Gil. Development of tantalum scaffold for orthopedic applications produced by space-holder method. Materials & Design 83 (2015) 112-119. doi: j.matdes.2015.05.067

  11. R. Fraioli, F. Rechenmacher, S. Neubauer, J.M. Manero, J. Gil, H Kessler, C. Mas-Moruno. Mimicking bone extracellular matrix: Integrin-bindingpeptidomimetics enhance osteoblast-like cells adhesion,proliferation, and differentiation on titanium. Colloids and Surfaces B: Biointerfaces. 128, 2015, 191-200. doi:10.1016/j.colsurfb.2014.12.057

  12. C. Herranz-Diez, Q. Li, C. Lamprecht, C. Mas-Moruno, S. Neubauer, H. Kessler, J.M. Manero, J. Guillem-Martí, C. Selhuber-Unkel. Bioactive compounds immobilized on Ti and TiNbHf: AFM-basedinvestigations of biofunctionalization efficiency and cell adhesion. Colloids and Surfaces B: Biointerfaces 136 (2015) 704-711. 2015.10.008

  13. M.I. Castellanos, A-S. Zenses, A. Grau, J.C. Rodríguez-Cabello, F.J Gil, J.M. Manero, M. Pegueroles. Biofunctionalization of REDV elastin-like recombinamers improves endothelialization on CoCr alloy surfaces for cardiovascular applications. Colloids and Surfaces B: Biointerfaces 127 (2015) 22-32. doi: 10.1016/j.colsurfb.2014.12.056

  14. S. Lee, H. Yun, R.A. Perez, S. Gallinetti, M. Ginebra, S. Choi, E. Kim and H. Kim. Nanotopological-Tailored Calcium Phosphate Cements for the Odontogenic Stimulation of Human Dental Pulp Stem Cells through Integrin Signaling. RSC Adv., 2015, 5, 63363. doi: 10.1039/C5RA11564G

  15. E.Cuzmar, R.A. Perez, M.C. Manzanares, M.P.Ginebra, J.Franch. In vivo osteogenic potential of biomimetic hydroxyapatite/collagen microspheres: comparison with injectable cement pastes. PLoS One. 2015 Jul 1;10(7):e0131188. doi: 10.1371/journal.pone.0131188

  16. G. Mestres, M. Espanol, W. Xia, C. Persson, M.P Ginebra, M. Karlsson Ott. Inflammatory Response to Nano and Microstructured Hydroxyapatite. PLoS ONE 10(4): e0120381 (2015). doi:10.1371/journal.pone.0120381

  17. J. Guillem-Marti, C. Herran-Diez, J.E. Shaffer, F.J. Gil, J.M. Manero. Mechanical and microstructural characterization of new nickel-free low modulus β-type titanium wires during thermomechanical treatments. Materials Science and Engineering A 636 (2015) 507-515. doi:10.1016/j.msea.2015.03.060

  18. C. Mas-Moruno, B. Garrido, D. Rodriguez, E. Ruperez, F.J. Gil. Biofunctionalization strategies on tantalum-based materials for osseointegrative applications. J Mater Sci: Mater Med (2015) 26:109. doi: 10.1007/s10856-015-5445-z

  19. B. Bullon, E.F. Bueno, M. Herrero, A. Fernandez-Palacin, J.V. Rios, P. Bullon, F.J. Gil. Effect of irrigation and stainless steel drills on dental implant bed heat generation. J Mater Sci: Mater Med (2015) 26:75. doi: 10.1007/s10856-015-5412-8

  20. C. Öhman, J. Unosson, E. Carlsson, M.P. Ginebra, C. Persson, H. Engqvist. Porosity prediction of calcium phosphate cements based on chemical composition. J Mater Sci Mater Med. 2015 Jul;26(7):210

  21. D. Martin-Gili, M. Molmeneu, M. Fernandez, M. Punset, Ll. Giner, J. Armengou, F. Javier Gil. Determination of fluid leakages in the different screw-retained implant-abutment connections in a mechanical artificial mouth. J Mater Sci Mater Med. 2015 Jul;26(7):211. doi: 10.1007/s10856-015-5544-x

  22. J. Buxadera-Palomero, C. Canal, S. Torrent-Camarero, B. Garrido, F.J. Gil, D. Rodríguez. Antifouling coatings for dental implants: Polyethylene glycol-like coatings on titanium by plasma polymerization. Biointerphases (2015); 10(2):029505. doi: 10.1116/1.4913376

  23. E. Fernandez-Garcia, J. Guillem-Marti, C.F. Gutierrez-Gonzalez, A. Fernandez, M.P. Ginebra, S.Lopez-Esteban. Osteoblastic cell response to spark plasma-sintered zirconia/titanium cermets. J Biomater Appl. 2015 Jan;29(6):813-23. doi: 10.1177/0885328214547400

  24. C. Persson, E. Robert, E. Carlsson, C. Robo, A. López, M. Godoy-Gallardo, M.P. Ginebra, H. Engqvist. The effect of unsaturated fatty acid and triglyceride oil addition on the mechanical and antibacterial properties of acrylic bone cements. J Biomater Appl. 2015 Sep;30(3):279-89. doi: 10.1177/0885328215581316

  25. Ajaxon, Y. Maazouz, M.P. Ginebra, C. Öhman, C. Persson. Evaluation of a porosity measurement method for wet calcium phosphate cements. J Biomater Appl. 2015 Nov;30(5):526-36. doi: 10.1177/0885328215594293

  26. C. Herranz-Diez, F.J. Gil, J. Guillem-Marti, J.M. Manero. Mechanical and physicochemical characterization along with biological interactions of a new Ti25Nb21Hf alloy for bone tissue engineering. Journal of Biomaterials Applications 30(2) 171-181. doi: 10.1177/0885328215577524



  1. C. Mas-Moruno, R. Fraioli, F. Albericio, JM. Manero, FJ. Gil. A novel peptide-based platform for the dual presentation of biologically-active peptide motifs on biomaterials. ACS Appl Mater Interfaces. 6 (2014):6525-36. doi: 10.1021/am5001213

  2. M. Godoy-Gallardo, C. Mas-Moruno, M. C. Fernández-Calderón, C. Pérez-Giraldo, J.M. Manero, F. Albericio, F.J. Gil, D. Rodriguez. Covalent Immobilization of hLf1-11 Peptide onto Titanium Surface Reduces Bacterial Adhesion and Biofilm Formation. Acta Biomaterialia. 10(2014):3522-34. doi: 10.1016/j.actbio.2014.03.026

  3. Y. Maazouz, E.B. Montufar, J. Guillem-Marti, I. Fleps, C. Öhman, C. Persson, M.P. Ginebra. Robocasting of biomimetic hydroxyapatite scaffolds using self-setting inks. J Mater Chem B. 2014, 2, 5378-86. doi: 10.1039/C4TB00438H

  4. M. Espanol, Z. Zhao, J. Almunia, M.P. Ginebra. Calcium phosphate neuron-like structures: a rare case or a common structure? J. Mater. Chem. B, 2014, 2 (14), 2020-2029. doi: 10.1039/C3TB21524E

  5. E. Veronesi, A. Murgia, A. Caselli, G. Grisendi, M.S. Piccinno, V.Rasini, R. Giordano, T. Montemurro, P. Bourin, L. Sensebè, M.T. Rojewski, H. Schrezenmeier, P. Layrolle, M.P. Ginebra, C. Bunu Panaitescu, E. Gómez-Barrena, F. Catani, P. Paolucci, J.S. Burns, M. Dominici. Transportation Conditions for Prompt Use of Ex-vivo Expanded Freshly Harvested Clinical Grade MSC For Bone Regeneration. Tissue Engineering A 20 (2014) 239-251, doi:10.1089/ten.tec.2013.0250. doi: 10.1089/ten.TEC.2013.0250

  6. E. Salvagni, G. Berguig, E. Engel, J.C. Rodriguez-Cabello, G.S. Coullerez, M. Textor, J.A. Planell, F.J. Gil, C. Aparicio. A Bioactive Elastin-like Recombinamer Reduces Unspecific Protein Adsorption and Enhances Cell Response on Titanium Surfaces. Colloids Surf B Biointerfaces. 114 (2014):225-33. doi: 10.1016/j.colsurfb.2013.10.008

  7. N. Marín-Pareja, E. Salvagni, J. Guillem-Marti, C. Aparicio, M.P. Ginebra. Collagen-functionalised titanium surfaces for biological sealing of dental implants: effect of immobilisation process on fibroblasts response. Colloids Surf B Biointerfaces. 2014 Oct 1;122:601-10. doi: 10.1016/j.colsurfb.2014.07.038

  8. M. Godoy-Gallardo, A.G. Rodríguez-Hernandez, L.M. Delgado, J.M. Manero, F.J. Gil, D. Rodríguez. Silver deposition on titanium surface by electrochemical anodizing process reduces bacterial adhesion of Streptococcus sanguinis and Lactobacillus salivarius. Clin. Oral Impl. Res. 0, 2014 / 1-10. doi: 10.1111/clr.12422

  9. Gil, FJ., Espinar, E., Llamas, JM., Sevilla, P. Fatigue life of bioactive titanium dental implants treated by means of Grit Blasting and Thermo-Chemical treatment. Clinical Implant Dentistry and Related Research. 16 (2014), 273-281. doi: 10.1111/j.1708-8208.2012.00468.x

  10. C. Caparros, J. Guillem-Martí, M. Punset, M. Molmeneu, J. Calero, FJ. Gil. Mechanical properties and in vitro biological response to porous titanium alloys for intervertebrae implants. Journal of the Mechanical Behavior of Biomedical Materials. 39, 2014; 79-86. doi: 10.1016/j.jmbbm.2014.05.029

  11. E. S. Sanzana, M. Navarro, M. P. Ginebra, J. A. Planell, H. A. Montecinos, A. C. Ojeda, V. A. Contreras. Role of porosity and pore architecture in the in vivo bone regeneration capacity of biodegradable glass scaffolds. J Biomed Mater Res A 102A (2014):1767-73. doi: 10.1002/jbm.a.34845

  12. M. González, J. Peña, F.J. Gil, J.M. Manero. Low modulus Ti-Nb-Hf alloy for biomedical applications. Materials Science and Engineering C 42 (2014) 691-695. doi: 10.1016/j.msec.2014.06.010

  13. J.C. Valera, E. Espinar, JM. Llamas, JM. Manero, E. Ruperez, FJ. Gil. Mechanical Properties of a New Superelastic Polymer Orthodontic Archwire. Mater Sci Eng C Mater Biol Appl. 2014 Sep 1;42:1-6. doi: 10.1016/j.msec.2014.05.008

  14. G. Mestres, F. S. Aguilera, N. Manzanares, R. Osorio, M. Toledano, M.P. Ginebra. Magnesium phosphate cements for endodontic applications with improved long-term sealing ability. International Endodontic Journal, 47, 127-139, 2014. 12123. doi: 10.1111/iej.12123

  15. F. Rechenmacher, K. Steigerwald, B. Laufer, S. Neubauer, T. G. Kapp, L. Li, C. Mas-Moruno, M. Joner, H. Kessler. The Integrin Ligand c(RGDf(NMe)Nal) Reduces Neointimal Hyperplasia in a Polymer-Free Drug-Eluting Stent System. ChemMedChem. 2014 Jul;9(7):1413-8. doi: 10.1002/cmdc.201400078

  16. L. Morejón-Alonso, J.A. Delgado García-Menocal, M. Tarragó Aymerich, J. A. Alvarez Guichard, M. García-Vallés, S. Martínez Manent, M.P. Ginebra. Calcium Phosphate Glasses: Silanation process and effect on the bioactivity behavior of Glass-PMMA composites. J Biomed Mater Res B Appl Biomater. 102(2014):205-13. doi: 10.1002/jbm.b.32996

  17. V. Paredes, E. Salvagni, E. Rodríguez-Castellon, F. J. Gil, J. M. Manero. Study on the use of 3-aminopropyltriethoxysilane and 3-chloropropyltriethoxysilane to surface biochemical modification of a novel low elastic modulus Ti-Nb-Hf alloy. J Biomed Mater Res Part B: Appl Biomater. 2014 Jun 9. doi: 10.1002/jbm.b.33226

  18. C. Labay, J. M. Canal, A. Navarro, C. Canal. Corona plasma modification of PA 66 for the design of textile delivery systems for cosmetic therapy. Applied Surface Science (2014) 316:251-258. DOI: 10.1016/j.apsusc.2014.07.191

  19. S. Gallinetti, C. Canal, M. P. Ginebra. Development and Characterization of Biphasic Hydroxyapatite/b-TCP Cements. J. Am. Ceram. Soc., 1-9 (2014). doi:  10.1111/jace.12861

  20. FJ. Gil, M. Herrero, P. Lázaro, J.V. Rios. Implant-abutment connections: influence of the design on the microgap and their fatigue and fracture behavior of dental implants. Journal of Materials Science: Materials in Medicine. Volume 25, Issue 7 (2014), Page 1825-1830. doi: 10.1007/s10856-014-5211-7

  21. V. Paredes, E. Salvagni , E. Rodriguez, J. Gil, J.M. Manero. Assessment and comparison of surface chemical composition and oxide layer modification upon two different activation methods on a CoCrMo alloy. J Mater Sci Mater Med. 2014 Feb;25(2):311-20. doi: 10.1007/s10856-013-5083-2

  22. L.A. Bravo, A. González de Cabañes, JM. Manero, E. Rupérez, FJ. Gil. NiTi superelastic orthodontic archwires with polyamide coating. J Mater Sci Mater Med. 2014 Feb;25(2):555-60. doi: 10.1007/s10856-013-5070-7

  23. M. Dessì, M.A. Alvarez-Perez, R. De Santis, M.P. Ginebra, J.A. Planell, L. Ambrosio. Bioactivation of calcium deficient hydroxyapatite with foamed gelatin gel. A new injectable self-setting bone analogue. doi: 10.1007/s10856-013-5071-6. J Mater Sci Mater Med 25(2014):283-95. doi: 10.1007/s10856-013-5071-6

  24. C. Canal, S. Gallinetti, M.P. Ginebra. Low pressure plasma treatment of polylactide fibres for enhanced mechanical performance of fibre-reinforced calcium phosphate cements. Plasma Processes and Polymers 11 (2014), 694-703. doi: 10.1002/ppap.201400018

  25. FJ Gil, N. Manzanares, A. Badet, C. Aparicio, MP Ginebra. Biomimetic treatment on dental implants for short -term bone regeneration. Clin Oral Investig. 2014 Jan;18(1):59-66. doi: 10.1007/s00784-013-0953-z

  26. S. Manso, G. Mestres, M.P. Ginebra, N. De Belie, I. Segura, A. Aguado. Development of a low pH cementitious material to enlarge bioreceptivity. Construction and Building Materials 54 (2014): 485-495. doi:10.1016/j.conbuildmat.2014.01.001

  27. M. Fernández, L. Delgado, M. Molmeneu, D. García, D. Rodríguez. Analysis of the misfit of dental implant-supported prostheses made with three manufacturing processes. Journal Prosthet. Dent. 2014 Feb;111(2):116-23. doi: 10.1016/j.prosdent. 2013.09.006. ISSN: 0022-3913

For full papers, please follow the link in FUTUR (UPC).