BBT's Publications during the last 5 years


  1. M.  Mateu-Sanz, C.V. Fuenteslópez, J. Uribe-Gomez, H.J. Haugen, A. Pandit, M.P. Ginebra, O. Hakimi, M. Krallinger, A. Samara. Redefining biomaterial biocompatibility: challenges for artificial intelligence and text mining. Trends in Biotechnology, 2408 No. of Pages 16. doi: OPEN ACESS.

  2. M. Živanić, A. Espona-Noguera, A. Lin C. Canal. Current State of Cold Atmospheric Plasma and Cancer-Immunity Cycle: Therapeutic Relevance and Overcoming Clinical Limitations Using Hydrogels(open in new window). Adv. Sci.2023, 2205803. doi: OPEN ACCESS.

  3. J. Whisler, S. Shahreza, K. Schlegelmilch, N. Ege, Y. Javanmardi, A. Malandrino, A. Agrawal, A. Fantin, B. Serwinski, H. Azizgolshani, C. Park, V. Shone, O.O. Demuren, A. del Rosari3, V.L. Butty, N. Holroyd, M.C. Domart, S. Hooper, N. Szita, L.A. Boyer, S. Walker-Samuel, B. Djordjevic, G.K. Sheridan, L. Collinson, F. Calvo, C. Ruhrberg, E. Sahai, R. Kamm, E. Moeendarbary. Emergent mechanical control of vascular morphogenesis. Science advances, 11 Agost 2023, vol. 9, núm. 32. doi: 10.1126/sciadv.adg9781. OPEN ACCESS.

  4. J. Tornín, M. Mateu-Sanz, V. Rey, D. Murillo, C. Huergo, B. Gallego, A. Rodriguez, R. Rodríguez, C. Canal. Cold plasma and inhibition of STAT3 selectively target tumorigenicity in osteosarcoma. Redox Biology, 2023, 102685. doi: // OPEN ACCESS.

  5. V. Chausse, E. Casanova-Batlle. Canal, M.P. Ginebra, J. Ciurana, M. Pegueroles. Solvent-cast direct-writing and electrospinning as a dual fabrication strategy for drug-eluting polymeric bioresorbable stents. Additive Manufacturing, Volume 71, 5 June 2023, 103568. doi: OPEN ACCESS.

  6. G. Junot, C. Calero, J. García-Torres, I. Pagonabarraga, P. Tierno. Unveiling the Rolling to Kayak Transition in Propelling Nanorods with Cargo Trapping and Pumping. Nano Lett. 2023, 23, 3, 850–857. 

  7. A. Heras-Parets, M.-P. Ginebra, J. M. Manero, J. Guillem-Marti. Guiding Fibroblast Activation Using an RGD-Mutated Heparin Binding II Fragment of Fibronectin for Gingival Titanium Integration. Adv. Healthcare Mater. 2023, 2203307 2203307. doi: 10.1002/adhm.202203307. OPEN ACCESS.

  8. J.O. Corvi, A. McKitrick, J.M. Fernández, C.V. Fuenteslópez, J.L. Gelpí, M.P. Ginebra, S. Capella-Gutierrez, O. Hakimi. DEBBIE: The Open Access Database of Experimental Scaffolds and Biomaterials Built Using an Automated Text Mining Pipeline. Adv. Healthcare Mater.2023, 2300150. doi: OPEN ACCESS.

  9. C. García-Mintegui, I. Goncharov, L. Ortiz-Membrado, E. Jiménez-Piqué, M.P. Ginebra, M. Vedani, J.L. Cortina, M. Pegueroles. Influence of ECAP process on mechanical, corrosion and bacterial properties of Zn-2Ag alloy for wound closure devices. Materials & Design, Volume 228, 2023, 111817. doi: OPEN ACCESS.

  10. L.P. Macor, S. Colombi, J.L. Tamarit, E. Engel, M.M. Pérez-Madrigal, J. García-Torres, C. Alemán. Immediate-sustained lactate release using alginate hydrogel assembled to proteinase K/polymer electrospun fibers. International Journal of Biological Macromolecules, Volume 238, 31 May 2023, 124117. doi:

  11. D. Piñera-Avellaneda, J. Buxadera-Palomero, M.P. Ginebra, J.A. Calero, J.M. Manero, E. Rupérez. Surface competition between osteoblasts and bacteria on silver-doped bioactive titanium implant. Biomaterials Advances Volume 146, March 2023, 213311. OPEN ACCESS.

  12. S. Gonzalez Gomez, J. Guillem-Marti, H. Martín-Gomez, C. Mas-Moruno, M.P. Ginebra, F.J. Gil, R.I. Barraquer, J.M. Manero. Titanium Boston keratoprosthesis with corneal cell adhesive and bactericidal dual coating. Biomaterials Advances 154 (2023) 213654. doi:  OPEN ACCESS.

  13. J. Tornín, B. Gallego, V. Rey, D. Murillo, C. Huergo, A. Rodríguez, C. Canal, R. Rodríguez. Cold plasma-treated medium preferentially eliminates doxorubicin-resistant osteosarcoma cells. Free Radical Biology and Medicine. Volume 209, Part 1, 20 November 2023, Pages 127-134. doi: OPEN ACCESS.

  14. C. García-Mintegui, V. Chausse, C. Labay, C. Mas-Moruno, M.p. Ginebra, J.L. Cortina, M. Pegueroles. Dual peptide functionalization of Zn alloys to enhance endothelialization for cardiovascular applications. Applied Surface Science Volume 645, 1 February 2024, 158900. doi: OPEN ACCESS.

  15. V. Chausse, C. Mas-Moruno, H. Martin-Gómez, M. Pino,d M. Díaz-Ricart, G. Escolar, M.P. Ginebra M. Pegueroles. Functionalization of 3D printed polymeric bioresorbable stents with a dual cell-adhesive peptidic platform combining RGDS and YIGSR sequences. Biomater. Sci., 2023, Advance Article. doi: 

  16. F. Tampieri, A. Espona-Noguera, C. Labay, M.-P. Ginebra, M. Yusupov, A. Bogaerts, C. Canal. Does non-thermal plasma modify biopolymers in solution? A chemical and mechanistic study for alginate. Biomater. Sci. April 2023.

  17. Ll. Oliver-Cervelló, H. Martin-Gómez, C. Gonzalez-Garcia, M. Salmeron-Sanchez, M.P. Ginebra, C. Mas-Moruno. Protease-degradable hydrogels with multifunctional biomimetic peptides for bone tissue engineering. Front. Bioeng. Biotechnol. (2023) 11:1192436. doi: 10.3389/fbioe.2023.1192436. OPEN ACCESS.

  18. N. Pien, D. Di Francesco, F. Copes, M. Bartolf-Kopp, V. Chausse, M. Meeremans, M. Pegueroles 6 , T. Jüngst, C. De Schauwer, F. Boccafoschi, P. Dubruel, S. Van Vlierberghe, D. Mantovani. Polymeric reinforcements for cellularized collagen-based vascular wall models: influence of the scaffold architecture on the mechanical and biological properties. Front. Bioeng. Biotechnol. 11:1285565. doi: 10.3389/fbioe.2023.1285565. OPEN ACCESS.

  19. N. García-de-Albeniz, E. Jiménez-Piqué, J.J. Roa, C. Mas-Moruno. A review of surface topographical modification strategies of 3Y-TZP: Effect in the physicochemical properties, microstructure, mechanical reliability, and biological response. Journal of the European Ceramic Society, Volume 43, Issue 8, 2023 Pages 2977-3004. doi: OPEN ACCESS.

  20. D. Moreno, J. Buxadera-Palomero, M.P. Ginebra, J.M. Manero, H. Martin-Gómez,C. Mas-Moruno, D.Rodríguez. Comparison of the Antibacterial Effect of Silver Nanoparticles and a Multifunctional Antimicrobial Peptide on Titanium Surface. Int. J. Mol. Sci. 2023, 24, 9739. doi: OPEN ACCESS.

  21. A. Rodríguez-Contreras, D. Torres, D. Piñera-Avellaneda, Ll. Pérez-Palou, M. Ortiz-Hernández, M.P. Ginebra, J.A. Calero, J.M. Manero, E. Rupérez. Dual-Action Effect of Gallium and Silver Providing Osseointegration and Antibacterial Properties to Calcium Titanate Coatings on Porous Titanium Implants. Int. J. Mol. Sci. 2023, 24, 8762. doi: OPEN ACCESS.

  22. J. Guillem-Marti, E. Vidal, A. Girotti, A. Heras-Parets, D. Torres, J.F. Arias, M.P. Ginebra, J.C. Rodriguez-Cabello, J.M. Manero. Functionalization of 3D-Printed Titanium Scaffolds with Elastin-like Recombinamers to Improve Cell Colonization and Osteoinduction. Pharmaceutics 2023, 15, 872. doi: // OPEN ACCESS

  23. C.V. Fuenteslópez, A. McKitrick, J. Corvi, M.P. Ginebra, O. Hakimi. Biomaterials text mining: A hands-on comparative study of methods on polydioxanone biocompatibility. New Biotechnology, Volume 77, 25 November 2023, Pages 161-175. doi: OPEN ACCESS.

  24. M. Espanol, E. Davis, E. Meslet, G. Mestres, E.B. Montufar, M.P Ginebra. Effect of moisture on the reactivity of alpha-tricalcium phosphate. Ceramics International, Volume 49, Issue 11, Part B, 1 June 2023, Pages 18228-18237. doi: // ISSN: 0272-8842. OPEN ACCESS.

  25. N. Garcia-de-Albeniz, M.-P. Ginebra, E. Jimenez-Piqué, J.J. Roa, C. Mas-Moruno. Influence of nanosecond laser surface patterning on dental 3Y-TZP: Effects on the topography, hydrothermal degradation and cell response. Dental Materials. 2023 Nov 9:S0109-5641(23)00438-4. doi: 10.1016/ OPEN ACCESS.

  26. M. Herrero-Climent, M. Punset, M. Molmeneu,A Brizuela, J. Gil. Differences between the Fittings of Dental Prostheses Produced by CAD-CAM and Laser Sintering Processes. J. Funct. Biomater. 2023, 14(2), 67; OPEN ACCESS
  27. S. Colombi, L.P. Macor, L. Ortiz-Membrado, S. Pérez-Amodio, E. Jiménez-Piqué, E. Engel, M.M. Pérez-Madrigal, J. García-Torres, C. Alemán. Enzymatic Degradation of Polylactic Acid Fibers Supported on a Hydrogel for Sustained Release of Lactate. ACS Appl. Bio Mater. 2023, 6, 9, 3889–3901. doi:

  28. X. Solé-Martí, C. Labay, Y. Raymond, J. Franch, R. Benitez, M.P. Ginebra, C. Canal. Ceramic-hydrogel composite as carrier for cold-plasma reactive-species: Safety and osteogenic capacity in vivo. Plasma Process Polym. Volume 20, Issue 1, Jan 2023. OPEN ACCESS.

  29. F. Tampieri, Y. Gorbanev, E. Sardella. Plasma‐treated liquids in medicine: Let's get chemical. Plasma Process Polym. 2023;e2300077. doi: OPEN ACCESS.

  30. C. Canal, A. Espona-Noguera, F. Tampieri. Special issue: Plasma Medicine - part I. Plasma Process. Polym., Vol 20, September 2023, e2370019. doi: 10.1002/ppap.202370019.OPEN ACCESS, EDITORIAL & COVER.

  31. C. Bucci, F. Tampieri, M. Mateu-Sanz, R. Laurita, V. Colombo, C. Canal. Oxidation of lactate to pyruvate mediates the cytotoxic potential of physical plasma-treated saline solutions in ovarian cancer. Plasma Process. Polym., e2300093. doi: 10.1002/ppap.202300093. OPEN ACCESS.

  32. X. Wang, J. Guillem, D. Lee, A. Hinck, R. Beth, D. Baker. De novo design of BMP mimics. Biophysical Journal, Volume 122, Issue 3, Supplement 1, 312A, 2023. doi:

  33. Q. Liu, I. Lodoso-Torrecilla, R. Klein Gunnewiek, H.R. Harhangi, A.G. Mikos, Laura van Niftrik, J.A. Jansen 4 5, L. Chen, J. JJP. van den Beucken. Tunable calcium phosphate cement formulations for predictable local release of doxycycline. Materialia (2023), 101769. doi: //

  34. D. Herrera, I. Lodoso-Torrecilla, M.P. Ginebra, K. Rappe, J. Franch. Osteogenic differentiation of adipose-derived canine mesenchymal stem cells seeded in porous calcium-phosphate scaffolds. Front. Vet. Sci., 02 June 2023, Sec. Veterinary Regenerative Medicine, Volume 10 – 2023. doi: OPEN ACCESS.


    1. Ll. Oliver-Cervelló, H. Martin-Gómez, N. Mandakhbayar, Y.W. Jo, E.A. Cavalcanti-Adam, H.W. Kim, M.P. Ginebra, J.H. Lee,C. Mas-Moruno. Mimicking Bone Extracellular Matrix: From BMP-2-Derived Sequences to Osteogenic-Multifunctional Coatings. Adv. Healthcare Mater. 2022, 2201339. doi: 10.1002/adhm.202201339. OPEN ACCESS.

    2. A. Przekora, L. Penolazzi, G. Kalisz, P. Kazimierczak, C. Canal, M. Wojcik, R. Piva, A. Sroka-Bartnicka. Osteoclast-mediated acidic hydrolysis of thermally gelled curdlan component of the bone scaffolds: Is it possible? Carbohydrate Polymers, Volume 295, 2022, 119914. doi: OPEN ACCESS.

    3. M. Bohner, Y. Maazouz, M.P. Ginebra, P. Habibovic, J.G. Schoenecker, H. Seeherman, J. van den Beucken, F. Witte. Sustained local ionic homeostatic imbalance caused by calcification modulates inflammation to trigger heterotopic ossification. Acta Biomater. 2022 Apr 6:S1742-7061(22)00197-0. doi: 10.1016/j.actbio.2022.03.057. OPEN ACCESS.

    4. Y. Raymond, C. Lehmann, E. Thorel, R. Benitez, A. Riveiro, J. Pou, M.C. Manzanares, J. Franch, C. Canal, M.P. Ginebra. 3D printing with star-shaped strands: A new approach to enhance in vivo bone regeneration, Biomaterials Advances, Volume 137 (2022) 212807. doi :// OPEN ACCESS.

    5. M. Iglesias-Fernandez, J. Buxadera-Palomero, J.M. Sadowska, M. Espanol, M.P. Ginebra, Implementation of bactericidal topographies on biomimetic calcium phosphates and the potential effect of its reactivity, Biomaterials Advances, 2022, 212797. doi: OPEN ACCESS.

    6. M. Bonany, A.J. Pérez-Berná, T. Dučić, E. Pereiro, H. Martin-Gómez, C. Mas-Moruno, S. van Rijt. Zh. Zhao, M. Espanol, M.P. Ginebra. Hydroxyapatite nanoparticles-cell interaction: New approaches to disclose the fate of membrane-bound and internalised nanoparticles. Biomaterials Advances, Volume 142, November 2022, 213148. doi: ACCESS.

    7. A. Michalicha. A. Espona-Noguera, C. Canal, B. Budzyńska, M. Pięt, S. Przywara, J. Pawelec, A. Belcarz. Polycatecholamine and gentamicin as modifiers for antibacterial and blood-biocompatible polyester vascular prostheses. Materials Science & engineering. C, Materials for Biological Applications, 07 Jan 2022, :112645. doi:  

    8. S-S. D. Carter, A-R. Atif, A. Diez-Escudero, M. Grape, M.P. Ginebra, M. Tenje, G. Mestres. A microfluidic-based approach to investigate the inflammatory response of macrophages to pristine and drug-loaded nanostructured hydroxyapatite. Materials Today Bio, Volume 16, 2022, 100351. doi :// OPEN ACCESS.

    9. J.M. García-Torres, S. Colombi, L.P. Macor, C. Alemán. Multitasking smart hydrogels based on the combination of alginate and poly(3,4-ethylenedioxythiophene) properties: A review. International Journal of Biological Macromolecules 219 (2022) 312–332. doi: OPEN ACCESS.

    10. J.M. García-Torres, C. Lázaro, D. Sylla, S. Lanzalaco , M.P. Ginebra , C. Alemán . Combining 2D organic and 1D inorganic nanoblocks to develop free-standing hybrid nanomembranes for conformable biosensors. Journal of Nanostructure in Chemistry pp 1-11. doi: OPEN ACCESS

    11. M. Bonany, L. del-Mazo-Barbara, M. Espanol, M.P. Ginebra. Microsphere incorporation as a strategy to tune the biological performance of bioinks. Journal of Tissue Engineering. 2022;13. doi:10.1177/20417314221119895. OPEN ACCESS.

    12. M. Mateu-Sanz, M.P. Ginebra, J. Tornín, C. Canal. Cold atmospheric plasma enhances doxorubicin selectivity in metastasic bone cáncer. Free Radical Biology and Medicine 189 (2022) 32–41. doi: OPEN ACCESS.

    13. X. Solé-Martí, T. Vilella, C. Labay, F. Tampieri, M.P. Ginebra, C. Canal. Thermosensitive hydrogels to deliver reactive species generated by cold atmospheric plasma: a case study with methylcellulose. Biomater. Sci., 2022, 10,6. 3845. doi: OPEN ACCESS.

    14. K.S. Rappe, M. Ortiz, M. Punset, M. Molmeneu, A. Barba, C. Mas J. Guillem-Marti, C. Caparrós, E Rupérez, J. A. Calero, M.C. Manzanares, J. Gil, J. Franch. On-Growth and In-Growth Osseointegration Enhancement in PM Porous Ti-Scaffolds by two Different Bioactivation Strategies: Alkali Thermochemical Treatment and RGD Peptide Coating. Int. J. Mol. Sci. 2022;23(3), 1750. doi: OPEN ACCESS.

    15. A. Michalicha, C. Canal, A. Espona-Noguera, M. Piet, B. Budzyńska, S. Przywara, A. Belcarz. Collagen-Sealed Polyester Vascular Prostheses Functionalized by Polycatecholamine Coatings. International Journal of Molecular Sciences. 2022; 23(16):9369. doi:// OPEN ACCESS.

    16. M. Mak, A. Carlier, F. Spill, A. Malandrino, M. Long, M.J. Gomez-Benito. Editorial: Mechanobiology and the microenvironment: Computational and experimental approaches. Front. Cell Dev. Biol., 21 October 2022, Sec. Cell Adhesion and Migration, Volume 10 – 2022. doi: // ACCESS.

    17. R. Schieber, C. Mas-Moruno, F. Lasserre, J.J. Roa, M.P. Ginebra, F. Mücklich, M. Pegueroles. Effectiveness of Direct Laser Interference Patterning and Peptide Immobilization on Endothelial Cell Migration for Cardio-Vascular Applications: An In Vitro Study. Nanomaterials 2022, 12, 1217. doi: OPEN ACCESS.

    18. M. Widhe, A. Diez-Escudero, Y. Liu, N. Ringström, M.P. Ginebra, C. Persson, M. Hedhammar, G. Mestres. Functionalized silk promotes cell migration into calcium phosphate cements by providing macropores and cell adhesion motifs. Ceramics International, Volume 48, Issue 21, 2022, Pages 31449-31460. doi: // OPEN ACCESS.

    19. F. Mochi, E. Scatena, D. Rodriguez, M.P. Ginebra, C. del Gaudio. Scaffold-based bone tissue engineering in microgravity: potential, concerns and implications. npj Microgravity 8, 45 (2022). doi: OPEN ACCESS.

    20. V. Chausse, C. Iglesias, E. Bou-Petit, M.-P. Ginebra, M. Pegueroles. Chemical vs thermal accelerated hydrolytic degradation of 3D-printed PLLA/PLCL bioresorbable stents: Characterization and influence of sterilization, Polymer Testing 117 (2023) 107817. doi: OPEN ACCESS.

    21. Y. Raymond, L. Johansson, E. Thorel, M.P. Ginebra. Translation of three‑dimensional printing of ceramics in bone tissue engineering and drug delivery. MRS Bulletin 47, pages59–69 (2022). doi: 

    22. F. Tampieri, A. G. Araguz, C. Canal. Can we remove tattoos with non‐thermal atmospheric plasma? Plasma Process Polym. 2022;e2100188. doi: 10.1002/ppap.202100188. OPEN ACCESS.

    23. A. Muixí, S. Zlotnik, P. Calvet, M. Espanol, I. Lodoso-Torrecilla, M.P. Ginebra, P. Díez, A. García-González. A multiparametric advection-diffusion reduced-order model for molecular transport in scaffolds for osteoinduction. Biomechanics and Modeling in Mechanobiology volume 21, 1099–1115 (2022). OPEN ACCESS.

    24. P. Verdeguer, J. Gil, M. Punset, J.M. Manero, J. Nart, J. Vilarrasa, E. Ruperez. Citric Acid in the Passivation of Titanium Dental Implants: Corrosion Resistance and Bactericide Behavior. Materials. 2022; 15(2):545. OPEN ACCESS.

    25. M. Punset, A. Brizuela, E. Pérez-Pevida, M. Herrero-Climent, J.M. Manero, J. Gil. Mechanical Characterization of Dental Prostheses Manufactured with PMMA–Graphene Composites. Materials 2022, 15(15), 5391; doi: OPEN ACCESS.

    26. F. Arias-González, A. Rodríguez-Contreras, M. Punset, J.M. Manero, O. Barro, M. Fernández-Arias, F. Lusquiños J. Gil, J. Pou. Laser-Deposited Beta Type Ti-42Nb Alloy with Anisotropic Mechanical Properties for Pioneering Biomedical Implants with a Very Low Elastic Modulus. Materials 2022, 15, 7172. doi: ISSN: 1996-1944. OPEN ACCESS.

    27. I Adamovich, S Agarwal, E Ahedo, L L Alves, S Baalrud, N Babaeva, A Bogaerts, A Bourdon, P J Bruggeman, C Canal, E H Choi, S Coulombe, Z Donkó, D B Graves, S Hamaguchi, D Hegemann, M Hori, H-H Kim, G M W Kroesen, M J Kushner, A Laricchiuta, X Li, T E Magin, S Mededovic Thagard, V Miller, A B Murphy, G S Oehrlein, N Puac, R M Sankaran, S Samukawa, M Shiratani, M Šimek, N Tarasenko, K Terashima, E Thomas Jr, J Trieschmann, S Tsikata, M M Turner, I J van der Walt, M C M van de Sanden, T von Woedtke. The 2022 Plasma Roadmap: low temperature plasma science and technology. J. Phys. D: Appl. Phys. 55 (2022) 373001. doi:// OPEN ACCESS.

    28. N. Cruz, J. Gil, M. Punset, J.M. Manero, J.P. Tondela, P. Verdeguer, C. Aparicio, E. Rúperez. Relevant Aspects of Piranha Passivation in Ti6Al4V Alloy Dental Meshes. Coatings 2022, 12(2), 154; doi: ISSN: 2079-6412. OPEN ACCESS.

    29. A. Solà-Pérez, D. Pastorino, C. Aparicio, M. Pegueroles, R. Sannam-Khan, S. Wright, C. Ucer. Success Rates of Zygomatic Implants for the Rehabilitation of Severely Atrophic Maxilla: A Systematic Review. Dent. J. 2022, 10(8), 151. doi: OPEN ACCESS.



    1. J. Tornin, C. Labay, F. Tampieri, M.P. Ginebra, C. Canal. Evaluation of the effects of cold atmospheric plasma and plasma-treated liquids in cancer cell cultures. Nature Protocols volume 16, pages2826–2850 (2021). doi: OPEN ACCESS.

    2. C. García-Mintegui, L. C. Cordoba, J. Buxadera-Palomero, A. Marquina, E. Jimenez-Pique, M.P. Ginebra, J.L. Cortina, M. Pegueroles. Zn-Mg and Zn-Cu alloys for stenting applications: From nanoscale mechanical characterization to in vitro degradation and biocompatibility. Bioactive Materials Volume 6, Issue 12, December 2021, Pages 4430-4446. doi: OPEN ACCESS.

    3. Y. Raymond, E. Thorel, M. Liversain, A. Riveiro, J. Pou, M.P. Ginebra. 3D printing non-cylindrical strands: Morphological and structural implications. Additive Manufacturing, Volume 46, 2021, 102129. doi: OPEN ACCESS.

    4. V. Chausse, R. Schieber, Y. Raymond, B. Ségry, R. Sabaté, K. Kolandaivelu, M.P. Ginebra, M. Pegueroles. Solvent-cast direct-writing as a fabrication strategy for radiopaque stents. Additive Manufacturing, Volume 48, Part B, 2021, 102392. doi: OPEN ACCESS.

    5. J. Konka, M. Espanol, B.M. Bosch, E. de Oliveira, M.-P. Ginebra. Maturation of biomimetic hydroxyapatite in physiological fluids: a physicochemical and proteomic study. Materials Today Bio, Volume 12, 2021, 100137. OPEN ACCESS.

    6. I. Lodoso-Torrecilla, J.J.J.P. van den Beucken, J.A. Jansen. Calcium phosphate cements: Optimization toward biodegradability. Acta Biomater. 2021 Jan 1;119:1-12. doi: 10.1016/j.actbio.2020.10.013. OPEN ACCESS.

    7. J. Konka, J. Buxadera-Palomero, M. Espanol, M.P. Ginebra. 3D printing of hierarchical porous biomimetic hydroxyapatite scaffolds: Adding concavities to the convex filaments. Acta Biomaterialia Volume 134, 15 October 2021, Pages 744-759. doi: OPEN ACCESS.

    8. Y. Raymond, M. Bonany, C. Lehmann, E. Thorel, R. Benítez, J. Franch, M. Espanol, X. Solé-Martí, M.C. Manzanares, C. Canal, M.P. Ginebra. Hydrothermal processing of 3D-printed calcium phosphate scaffolds enhances bone formation in vivo: a comparison with biomimetic treatment. Acta Biomateriaia Volume 135, November 2021, Pages 671-688. doi: OPEN ACCESS.

    9. M.Á. Brennan, D.S. Monahan, B. Brulin, S. Gallinetti, P. lHumbert, Ch. Tringides, C. Canal, M.P. Ginebra, P. Layrolle. Biomimetic versus sintered macroporous calcium phosphate scaffolds enhanced bone regeneration and human mesenchymal stromal cell engraftment in calvarial defects. Acta Biomaterialia Volume 135, November 2021, Pages 689-704. doi:

    10. A. Puiggalí-Jou, I. Babeli, J.J. Roa, J.O. Zoppe, J. Garcia-Amorós, M.P Ginebra, C. Alemán, J. García-Torres. Remote Spatiotemporal Control of a Magnetic and Electroconductive Hydrogel Network via Magnetic Fields for Soft Electronic Applications. ACS Appl. Mater. Interfaces 2021, 13, 36, 42486–42501. doi: OPEN ACCESS.

    11. A. Rodriguez-Contreras, M. Punset, J.A. Calero, F.J. Gil, E. Ruperez, J.M. Manero. Powder metallurgy with space holder for porous titanium implants: A review. Journal of Materials Science & Technology Volume 76, 20 June 2021, Pages 129-149. doi: 

    12. O. Estupiñán, E. Niza, I. Bravo, V. Rey, J. Tornín, B. Gallego, P. Clemente-Casares, F. Moris, A. Ocaña, V. Blanco-Lorenzo, M.Rodríguez-Santamaría, A. Vallina-Álvarez, M.V. González, A. Rodríguez, D. Hermida-Merino, C. Alonso-Moreno, R. Rodríguez. Mithramycin delivery systems to develop effective therapies in sarcomas. Journal of Nanobiotechnology. 2021 Sep 6;19(1):267. doi: 10.1186/s12951-021-01008-x. OPEN ACCESS.

    13. A. Serrà, J. García-Torres. Electrochemistry: A basic and powerful tool for micro- and nanomotor fabrication and characterization. Applied Materials Today, Volume 22, 2021, 100939. doi: OPEN ACCESS.

    14. J. Minguela, D.W. Müller, F. Mücklich, L. Llanes, M.P. Ginebra, J.J. Roa, C. Mas-Moruno. Peptidic biofunctionalization of laser patterned dental zirconia: A biochemical-topographical approach. Materials Science and Engineering: C, Volume 125, June 2021, 112096. doi: OPEN ACCESS.

    15. J. Tornín, A. Villasante, X. Solé-Martí, M.P. Ginebra, C. Canal. Osteosarcoma tissue-engineered model challenges oxidative stress therapy revealing promoted cancer stem cell properties. Free Radical Biology and Medicine 164 (2021) 107–118. doi: OPEN ACCESS.

    16. I. Babeli, A. Puiggalí-Jou, J. Josep Roa, M.P. Ginebra, J. García-Torres, C. Aleman. Hybrid conducting alginate-based hydrogel for hydrogen peroxide detection from enzymatic oxidation of lactate. International journal of biological macromolecules, Volume 193, Part B, 15 December 2021, Pages 1237-1248. doi:

    17. F. Tampieri, M.P. Ginebra, C. Canal. Quantification of Plasma-Produced Hydroxyl Radicals in Solution and their Dependence on the pH. Anal. Chem., 2021. DOI: 10.1021/acs.analchem.0c04906. OPEN ACCESS.

    18. I. Babeli, G. Ruano, A. Puiggalí‐Jou, M.P. Ginebra, C. Alemán, J. Garcia‐Torres. Self‐Healable and Eco‐Friendly Hydrogels for Flexible Supercapacitors. Adv. Sustainable Syst. 2021, 2000273. doi: 10.1002/adsu.202000273.

    19. X. Solé-Martí, A. Espona-Noguera, M.P Ginebra, C. Canal. Plasma-Conditioned Liquids as Anticancer Therapies In Vivo: Current State and Future Directions. Cancers 2021, 13(3), 452; doi: OPEN ACCESS.

    20. L. Del-Mazo-Barbara, M.P. Ginebra. Rheological characterisation of ceramic inks for 3D direct ink writing: a review. Journal of the European Ceramic Society Volume 41, Issue 16, December 2021, Pages 18-33. doi: OPEN ACCESS.

    21. H. Martin-Gomez, Ll. Oliver-Cervello, I. Sanchez-Campillo, V. Marchan, M.P. Ginebra, C. Mas-Moruno. A versatile click chemistry-based approach for functionalizing biomaterials of diverse nature with bioactive peptides. Chem. Commun., 2021,57, 982-985. doi: 10.1039/d0cc07463b.

    22. G. Boix-Lemonche, J. Guillem-Marti, M. Lekka, F. D'Este, F. Guida, J.M. Manero, B. Skerlavaj. Membrane perturbation, altered morphology and killing of Staphylococcus epidermidis upon contact with a cytocompatible peptide-based antibacterial surface. Colloids and Surfaces B: Biointerfaces 203 (2021) 111745. doi:

    23. B. Tarabová, F. Tampieri, E. Maran, E. Marotta, A. Ostrihoňová, M. Krewing, Z. Machala. Chemical and Antimicrobial Effects of Air Non-Thermal Plasma Processing of Fresh Apple Juice with Focus on Safety Aspects. Foods. 2021; 10(9):2055. OPEN ACCESS.

    24. I. Hamouda, C. Labay, U. Cvelbar, MP. Ginebra, C. Canal. Selectivity of direct plasma treatment and plasma‑conditioned media in bone cancer cell lines. Scientific Reports (2021) 11:17521. doi: OPEN ACCESS.

    25. M. Mateu-Sanz, J. Tornín, M.P. Ginebra, C. Canal. Cold Atmospheric Plasma: A New Strategy Based Primarily on Oxidative Stress for Osteosarcoma Therapy. J. Clin. Med. 2021, 10, 893. doi: OPEN ACCESS.

    26. E. Vidal, J. Guillem-Marti, M.P. Ginebra, Ch. Combes, E. Ruperez, D. Rodriguez. Multifunctional homogeneous calcium phosphate coatings: Toward antibacterial and cell adhesive titanium scaffolds. Surface and Coatings Technology, Volume 405, 15 January 2021, 126557. doi: 

    27. J. Orrit-Prat, R. Bonet, E. Rupérez, M. Punset, M. Ortiz-Hernández, J. Guillem-Marti, A. Lousa, D. Cano, C. Díaz, G. García Fuentes, J. Caro. Bactericidal silver-doped DLC coatings obtained by pulsed filtered cathodic arc co-deposition. Surface and Coatings Technology, Volume 411, 15 April 2021, 126977. doi:

    28. A. Rodríguez-Contreras, D. Torres, B. Rafik, M. Ortiz-Hernandez, M.P. Ginebra, J. A. Calero, J.M Manero, E. Ruperez. Bioactivity and antibacterial properties of calcium- and silver-doped coatings on 3D printed titanium scaffolds. Surface & Coatings Technology 421 (2021) 127476. doi:

    29. T. Martinez, M. Español, C. Charvillat, O. Marsan, M.P. Ginebra, C. Rey, S. Sarda. a-tricalcium phosphate synthesis from amorphous calcium phosphate: structural characterization and hydraulic reactivity. J Mater Sci (2021) 56:13509–13523. doi:

    30. J. Toledano-Serrabona, M.A. Sánchez-Garcés, C. Gay-Escoda, E. Valmaseda-Castellón, O. Camps-Font, P. Verdeguer, M. Molmeneu, F.J. Gil. Mechanical Properties and Corrosion Behavior of Ti6Al4V Particles Obtained by Implantoplasty: An In Vitro Study. Part II. Materials 2021, 14, 6519. doi: OPEN ACCESS.

    31. N. Arlucea, A. Brizuela-Velasco, M. Dieguez-Pereira, M. Punset, M.l Molmeneu, F. Sánchez-Lashera, H. deLlanos-Lanchares, Á. Álvarez-Arenal. Zirconia vs. Titanium Dental Implants: Primary Stability In-Vitro Analysis. Materials 2021, 14, 7886. doi: // OPEN ACCESS.

    32. Y. Raymond, D. Pastorino, I. Ginebreda, Y. Maazouz, M. Ortiz, M.C. Manzanares, M.P. Ginebra. Computed tomography and histological evaluation of xenogenic and biomimetic bone grafts in three-wall alveolar defects in minipigs. Clin Oral Investig. 2021 Dec;25(12):6695-6706. doi:

    33. M. Punset, J. Villarrasa, J. Nart, J.M. Manero, B. Bosch, R. Padrós, R.A. Perez, F.J. Gil. Citric Acid Passivation of Titanium Dental Implants for Minimizing Bacterial Colonization Impact. Coatings 2021, 11, 214. doi: OPEN ACCESS.

    34. D. Boehm, C. Canal. Application of Plasma Technology in Bioscience and Biomedicine. Appl. Sci. 2021, 11(16), 7203. doi: OPEN ACCESS.

    35. J. Buxadera-Palomero, K. Fricke, S. Reuter, F.J. Gil, D. Rodriguez, C. Canal. One-Step Liquid Phase Polymerization of HEMA by Atmospheric-Pressure Plasma Discharges for Ti Dental Implants. Appl. Sci. 2021, 11, 662. doi: OPEN ACCESS.

    36. R. Schieber, Y. Raymond, C. Caparrós, J. Bou, E. Herrero Acero, G.M. Guebitz, C. Canal, M. Pegueroles. Functionalization Strategies and Fabrication of Solvent-Cast PLLA for Bioresorbable Stents. Appl. Sci. 2021, 11, 1478. doi: OPEN ACCESS.

    37. F. Arias-González, A. Rodríguez-Contreras, M. Punset, J.M. Manero, O. Barro, M. Fernández-Arias, F. Lusquiños, F.J. Gil, J. Pou. In-Situ Laser Directed Energy Deposition of Biomedical Ti-Nb and Ti-Zr-Nb Alloys from Elemental Powders. Metals 2021, 11, 1205. doi: OPEN ACCESS.

    38. Ll. Oliver-Cervello, H. Martin-Gomez, C. Mas-Moruno. New trends in the development of multifunctional peptides tofunctionalize biomaterials. J Pep Sci. 2021;e3335. doi: OPEN ACCESS.



    1. O. Hakimi, M. Krallinger, M.P. Ginebra. Time to kick-start text mining for biomaterials. Nat Rev Mater (2020). doi:

    2. O. Hakimi, J.L. Gelpi, M. Krallinger, F. Curi, D. Repchevsky, M.P. Ginebra. The Devices, Experimental Scaffolds, and Biomaterials Ontology (DEB): A Tool for Mapping, Annotation, and Analysis of Biomaterials' Data. Adv. Funct. Mater. 2020, 1909910. doi: 10.1002/adfm.201909910.

    3. Ll. Oliver-Cervelló, H. Martin-Gómez, L. Reyes, F. Noureddine, E.A. Cavalcanti-Adam, M.P. Ginebra, C. Mas-Moruno. An Engineered Biomimetic Peptide Regulates Cell Behavior by Synergistic Integrin and Growth Factor Signaling. Adv. Heathcare Mat. 2020, 2001757. doi:

    4. C. Labay, M. Roldán, F. Tampieri, A. Stancampiano, P. Escot Bocanegra, M.-P. Ginebra, C. Canal, Enhanced Generation of Reactive Species by Cold Plasma in Gelatin Solutions for Selective Cancer Cell Death, ACS Appl. Mater. Interfaces, 2020, 12, 42, 47256–47269. doi:

    5. P. Kazimierczak, A. Benko, K. Palka, C. Canal, D. Kolodynska, A. Przekora. Novel synthesis method combining a foaming agent with freeze-drying to obtain hybrid highly macroporous bone scaffolds. Journal of Materials Science & Technology, Volume 43, 15 April 2020, Pages 52-63. doi:

    6. I. Babeli, G. Ruano, J. Casanovas, M.P. Ginebra. García-Torres, C. Alemán. Conductive, self-healable and reusable poly(3,4-ethylenedioxythiophene)-based hydrogels for highly sensitive pressure arrays.                J. Mater. Chem. C, 2020,8, 8654-8667. doi: 10.1039/d0tc01947j.

    7. M. Mateu-Sanz, J Tornín, B. Brulin, A. Khlyustova, M.P. Ginebra , P. Layrolle, C. Canal. Cold Plasma-Treated Ringer's Saline: A Weapon to Target Osteosarcoma, Cancers 2020, Vol. 12, Page 227, vol. 12, no. 1, p. 227 doi: 10.3390/cancers12010227.

    8. J. Sadowska, M.P.Ginebra. Inflammation and biomaterials: role of the immune response in bone regeneration by inorganic scaffolds. J Mater Chem B. 2020 Oct 28;8(41):9404-9427. doi: 10.1039/d0tb01379j.

    9. A. Przekora, M. Audemar, J. Pawlat, C, Canal, J.S. Thomann, C. Labay, M. Wojcik, M. Kwiatkowski, P. Terebun, G. Ginalska, S. Hermans, D. Duday. Positive Effect of Cold Atmospheric Nitrogen Plasma on the Behavior of Mesenchymal Stem Cells Cultured on a Bone Scaffold Containing Iron Oxide-Loaded Silica Nanoparticles Catalyst. Int. J. Mol. Sci. 2020, 21, 4738; doi:10.3390/ijms21134738.

    10. J. Camilleri, T. Arias Moliz, A. Bettencourt, J. Costa, F. Martins, D. Rabadijeva, D. Rodriguez, L. Visai, C. Combes, C. Farrugia,P. Koidis, C. Neves. Standardization of antimicrobial testing ofdental devices. Dental Materials Volume 36, Issue 3, March 2020, Pages e59-e73. doi:

    11. J. Minguela, S. Slawik, F. Mücklich, M.P. Ginebra, L. Llanes, C. Mas-Morunoa, J.J. Roa. Evolution of microstructure and residual stresses in gradually ground/polished 3Y-TZP. Journal of the European Ceramic Society 40 (2020) 1582–1591. doi:

    12. J. Minguela, M.P. Ginebra, L. Llanes, C. Mas-Moruno, J.J. Roa. Influence of grinding/polishing on the mechanical, phase stability and cell adhesion properties of yttria-stabilized zirconia. Journal of the European Ceramic Society, Volume 40, Issue 12, September 2020, Pages 4304-4314. doi://

    13. A. Puiggalí-Jou, E. Cazorla, G. Ruano, I. Babeli, M.P. Ginebra, J. García-Torres, C. Aleman. Electroresponsive Alginate-Based Hydrogels for Controlled Release of Hydrophobic Drugs. ACS Biomater. Sci. Eng. 2020, 6, 6228−6240. doi:

    14. I. Hamouda, C.Labay, M.P. Ginebra, E. Nicol, C. Canal. Investigating the atmospheric pressure plasma jet modification of a photo-crosslinkable hydrogel, Polymer, Volume 192, 27 March 2020, 122308. doi:

    15. L. Vidal, C. Kampleitner, S. Krissian, M.A. Brennan, O. Hoffmann, Y. Raymond, Y. Maazouz, M.P. Ginebra, P. Rosset, P. Layrolle. Regeneration of segmental defects in metatarsus of sheep with vascularized and customized 3D-printed calcium phosphate scaffolds. Scientific Reports (2020) 10:7068 |

    16. J. Buxadera-Palomero, M. Godoy-Gallardo, M. Molmeneu, M. Punset, F.J. Gil. Antibacterial Properties of Triethoxysilylpropyl Succinic Anhydride Silane (TESPSA) on Titanium Dental Implants. Polymers 2020, 12(4), 773. doi:

    17. A. Rodríguez-Contreras, D. Torres,c, J. Guillem-Marti, P. Sereno, M.P. Ginebra, J.A. Calero, J.M. Manero, E. Rupérez. Development of novel dual-action coatings with osteoinductive and antibacterial properties for 3D-printed titanium implants. Surface & Coatings Technology 403 (2020) 126381. doi: /

    18. H. Martin-Gómez, L. Oliver-Cervelló, J. Buxadera-Palomero, M.P. Ginebra, C. Mas-Moruno. Chemically Diverse Multifunctional Peptide Platforms with Antimicrobial and Cell Adhesive Properties. ChemBioChem 2020, 21, 1–7. doi:

    19. J. Buxadera-Palomero, K. Albó, F.J. Gil, C. Mas-Moruno, D. Rodríguez. Polyethylene Glycol Pulsed Electrodeposition for the Development of Antifouling Coatings on Titanium. Coatings 2020, 10(5), 456; doi:

    20. R. Padrós, M. Punset, M. Molmeneu, A. Brizuela-Velasco, M. Herrero-Climent, E. Rupérez, F.J. Gil. Mechanical Properties of CoCr Dental-Prosthesis Restorations made by Three Manufacturing Processes. Influence of the Microstructure and Topography. Metals 2020, 10, 788. doi:10.3390/met10060788.

    21. R. Padrós, L. Giner-Tarrida, M. Herrero-Climent, M. Punset, F.J. Gil. Corrosion Resistance and Ion Release of Dental Prosthesis of CoCr Obtained by CAD-CAM Milling, Casting and Laser Sintering. Metals 2020, 10, 827; doi:10.3390/met10060827.

    22. J. Franch, A. Barba, K. Rappe, Y. Maazouz, M.P Ginebra. Use of three-dimensionally printed β-tricalcium phosphate synthetic bone graft combined with recombinant human bone morphogenic protein-2 to treat a severe radial atrophic nonunion in a Yorkshire terrier. Veterinary Surgery. 2020;1–6. doi: 10.1111/vsu.13476.



    1. J. Guillem-Marti, M. Gelabert, A. Heras-Parets, M. Pegueroles,M.P Ginebra, J.M. Manero. RGD Mutation of the Heparin Binding II Fragment of Fibronectin for Guiding Mesenchymal Stem Cell Behavior on Titanium Surfaces. ACS Appl. Mater. Interfaces 2019, 11, 3666−3678. doi: 10.1021/acsami.8b17138

    2. M. Godoy-Gallardo, C. Labay, L. Hosta-Rigau. Tyrosinase-Loaded Multicompartment Microreactor toward Melanoma Depletion. ACS Appl. Mater. Interfaces, 2019, 11 (6), pp 5862–5876. doi: 10.1021/acsami.8b20275

    3. A. Barba, A. Diez-Escudero, M. Espanol, M. Bonany, J.M. Sadowska, J. Guillem-Marti, C. Öhman-Mägi, C. Persson, M.C. Manzanares, J. Franch, M.P. Ginebra. The impact of biomimicry in the design of osteoinductive bone substitutes: nanoscale matters. ACS ACS Appl. Mater. Interfaces 2019, 11, 8818−8830. doi: 10.1021/acsami.8b20749.

    4. J.M. Sadowska, F. Wei, J. Guo, J. Guillem-Marti, Z. Lin, M.-P. Ginebra, Yin Xiao. The effect of biomimetic calcium deficient hydroxyapatite and sintered β-tricalcium phosphate on osteoimmune reaction and osteogenesis. Acta Biomaterialia 96 (2019) 605–618. doi:

    5. R. Fraioli, S. Neubauer, F. Rechenmacher, B.M. Bosch, K. Dashnyam, J.H. Kim, R. A. Perez, H.W. Kim, F.J. Gil, M.P. Ginebra, J.M. Manero, H. Kessler, C. Mas-Moruno. Control of stem cell response and bone growth on biomaterials by fully non-peptidic integrin selective ligands. Biomater. Sci., 2019,7, 1281-1285. doi: 10.1039/c8bm01466c.

    6. M. Fernández-Arias, M. Boutinguiza, J. del Val, E. Medina, D. Rodríguez, A. Riveiro, R. Comesaña, F. Lusquiños, F.J. Gil, J. Pou. RE-irradiation of silver nanoparticles obtained by laser ablation in water and assessment of their antibacterial effect. Applied Surface Science 473 (2019) 548–554. . doi:

    7. M. Fernández-Yagüe, R. Perez-Antoñanzas, J.J. Roa, M. Biggs, F.J. Gil, M. Pegueroles. Enhanced osteoconductivity on electrically charged titanium implants treated by physicochemical surface modifications methods. Nanomedicine: Nanotechnology, Biology, and Medicine 18 (2019) 1– 10. doi: 

    8. M. Hoyos-Nogués, E. Falgueras-Batlle, M.P. Ginebra, J.M. Manero, J. Gil, C. Mas-Moruno. A Dual Molecular Biointerface Combining RGD and KRSR Sequences Improves Osteoblastic Functions by Synergizing Integrin and Cell-Membrane Proteoglycan Binding. Int. J. Mol. Sci. 2019, 20, 1429; doi:10.3390/ijms20061429.

    9. L. Vojtova, L. Michlovska, K. Valova, M. Zboncak, M. Trunec, K. Castkova, M. Krticka, V. Pavlinakova, P. Polacek, M. Dzurov, V. Lukasova, M. Rampichova, T. Suchy, R. Sedlacek, M.P. Ginebra, E.B. Montufar. The Effect of the Thermosensitive Biodegradable PLGA⁻PEG⁻PLGA Copolymer on the Rheological, Structural and Mechanical Properties of Thixotropic Self-Hardening Tricalcium Phosphate Cement.. Int J Mol Sci. 2019 Jan 17;20(2). pii: E391.doi: 10.3390/ijms20020391.

    10. J. Tornin, M. Mateu-Sanz, A. Rodríguez, C. Labay, R. Rodríguez, C. Canal. Pyruvate Plays a Main Role in the Antitumoral Selectivity of Cold Atmospheric Plasma in Osteosarcoma. Scientific Reportsvolume 9, Article number: 10681 (2019). doi: 

    11. A. Rodríguez-Contreras, J.i Guillem-Marti, O. Lopez, J.M. Manero, E. Ruperez. Antimicrobial PHAs coatings for solid and porous tantalum implants. Colloids and Surfaces B: Biointerfaces 182 (2019) 110317. doi:

    12. G. Boix-Lemonche, J. Guillem-Marti, F. D'Este, J.M. Manero, B. Skerlavaj. Covalent grafting of titanium with a cathelicidin peptide produces an osteoblast compatible surface with antistaphylococcal activity. Colloids and Surfaces B: Biointerfaces 185 (2020) 110586. doi:

    13. J. Guillem-Marti, N. Cinca, M. Punset, I. García Cano, F.J. Gil, J.M. Guilemany, S Dost. Porous titanium-hydroxyapatite composite coating obtained on titanium by cold gas spray with high bond strength for biomedical applications. Colloids and Surfaces B: Biointerfaces 180 (2019) 245–253. doi:

    14. C. Labay, I. Hamouda, F. Tampieri, M.P. Ginebra, C. Canal. Production of reactive species in alginate hydrogels for cold atmospheric plasma-based therapies. Scientific Reports, 9, 16160 (2019). doi:

    15. J.A. Picas, M. Punset, E. Rupérez, S. Menargues, E. Martin, M.T. Baile. Corrosion mechanism of HVOF thermal sprayed WC-CoCr coatings in acidic chloride media. Surface & Coatings Technology 371 (2019) 378–388. doi: ISNN: 0257-8972.

    16. A. Khlyustova, C. Labay, Z. Machala, M.P. Ginebra, C.Canal. Important parameters in plasma jets for the production of RONS in liquids for plasma medicine: a brief review. Frontiers of Chemical Science and Engineering. Doi:

    17. E. Vidal, J. Buxadera-Palomero, C. Pierre, J.M. Manero, M.P. Ginebra, S. Cazalbou, C. Combes, E. Rupérez, D. Rodriguez. Single-step pulsed electrodeposition of calcium phosphate coatings on titanium for drug delivery. Surface & Coatings Technology 358 (2019) 266–275. doi: 10.1016/j.surfcoat.2018.11.037. 

    18. A. Przekora, J. Pawlat, P. Terebun, D. Duday, C. Canal, S. Hermans, M. Audemar, C. Labay, J.-S. Thomann, G. Ginalska. The effect of low temperature atmospheric nitrogen plasma on MC3T3-E1 preosteoblast proliferation and differentiation in vitro. Journal of Physics D: Applied Physics (2019) 52: 275401. doi: 

    19. A. Diez‐Escudero, E. Torreggiani, G. Di Pompo, M. Espanol, C. Persson, G. Ciapetti, N. Baldini, M. Ginebra, Effect of calcium phosphate heparinization on the in vitro inflammatory response and osteoclastogenesis of human blood precursor cells, J. Tissue Eng. Regen. Med. 13 (2019) term.2872. doi:// 

    20. U. Cvelbar, J.L. Walsh, M. Černák, H.W. de Vries, S. Reuter, Th. Belmonte, C. Corbella, C. Miron, N. Hojnik, A. Jurov, H. Puliyalil, M. Gorjanc, S. Portal, R. Laurita, V. Colombo, J. Schäfer, A. Nikiforov, M. Modic, O. Kylian, M. Polak, C. Labay, J.M. Canal, C. Canal, M. Gherardi, K. Bazaka, P. Sonar, K.K. Ostrikov, D. Cameron, S. Thomas, K.D. Weltmann. White paper on the future of plasma science and technology in plastics and textiles. Plasma Process Polym.2019;16:e1700228. doi: 10.1002/ppap.201700228

    21. A. Brizuela, M. Herrero-Climent, E. Rios-Carrasco, J.V. Rios-Santos, R.A. Pérez, J.M. Manero, J. Gil Mur. Influence of the Elastic Modulus on the Osseointegration of Dental Implants. Materials 2019, 12, 980; doi:10.3390/ma12060980.

    22. A. Cirera , M.C. Manzanares , P. Sevilla, M. Ortiz-Hernandez, P. Galindo-Moreno, J. Gil. Biofunctionalization with a TGF-1 Inhibitor Peptide in the Osseointegration of Synthetic Bone Grafts: An In Vivo Study in Beagle Dogs. Materials 2019, 12, 3168; doi:10.3390/ma12193168.

    23. E. Velasco-Ortega, A. Flichy-Fernández, M. Punset, A. Jiménez-Guerra, J.M. Manero, J. Gil. Fracture and Fatigue of Titanium Narrow Dental Implants: New Trends in Order to Improve the Mechanical Response. Materials 2019, 12, 3728; doi: 10.3390/ma12223728.

    24. A. Hoornaert, Y. Maazouz, D. Pastorino, C. Aparicio, G. de Pinieux, B. H. Fellah, M.-P. Ginebra, P. Layrolle. Vertical bone regeneration with synthetic biomimetic calcium phosphate onto the calvaria of rats. Tissue Eng Part C Methods. 2019 Jan;25(1):1-11. doi: 10.1089/ten.TEC.2018.0260.

    25. E. Dávila, M. Ortiz-Hernández, R.A. Perez, M. Herrero-Climent, M. Cerrolaza, F.J. Gil. Crestal module design optimization of dental implants: finite element analysis and in vivo studies. Journal of Materials Science: Materials in Medicine (2019) 30:90. doi:



    1. J. M. Sadowska, F. Wei, J. Guo, J. Guillem-Marti, M.P. Ginebra, Y. Xiao. Effect of nano-structural properties of biomimetic hydroxyapatite on osteoimmunomodulation. Biomaterials 181 (2018) 318–332. doi:

    2. J.M. Sadowska, J. Guillem-Marti, M. Espanol, Ch. Stähli, N. Döbelin, M.P. Ginebra. In vitro response of mesenchymal stem cells to biomimetic hydroxyapatite substrates: A new strategy to assess the effect of ion exchange. Acta Biomaterialia 76 (2018) 319–332. doi: 10.1016/j.actbio.2018.06.025.

    3. A. Barba, Y. Maazouz, A. Diez-Escudero, K. Rappe, M. Espanol, E.B. Montufar, C. Öhman-Mägi, C. Persson, P. Fontecha, M.C. Manzanares, J. Franch, M.P. Ginebra. Osteogenesis by foamed and 3D-printed nanostructured calcium phosphate scaffolds: Effect of pore architecture. Acta Biomaterialia 79 (2018) 135–147. doi:

    4. S. Raymond, Y. Maazouz, E.B. Montufar, R.A. Perez, B. González, J. Konka, J. Kaiser, M.P. Ginebra. Accelerated hardening of nanotextured 3D-plotted self-setting calcium phosphate inks. Acta Biomaterialia 75 (2018) 451–462.

    5. A. Diez-Escudero, M. Espanol, X. Lu, C. Persson, M.-P. Ginebra. Heparinization of Beta Tricalcium Phosphate: Osteoimmunomodulatory Effects. Adv Healthc Mater. 2018 Mar;7(5). doi: 10.1002/adhm.201700867. 

    6. C. Mas-Moruno, B. Su, M.J. Dalby. Multifunctional Coatings and Nanotopographies: Toward Cell Instructive and Antibacterial Implants. Adv. Healthcare Mater. 2018, 1801103. doi: 10.1002/adhm.201801103.

    7. J.M. Sadowska, J. Guillem-Marti, M.-P. Ginebra. The influence of physicochemical properties of biomimetic hydroxyapatite on the in vitro behavior of endothelial progenitor cells and their interaction with mesenchymal stem cells. Adv. Healthcare Mater. 2018, 1801138. doi: 10.1002/adhm.201801138.

    8. G. Mestres, M.A. Fernandez-Yague, D. Pastorino, E.B. Montufar, C. Canal, M.C. Manzanares-Céspedes, M.P. Ginebra. In vivo efficiency of antimicrobial inorganic bone grafts in osteomyelitis treatments. Materials Science & Engineering C 97 (2019) 84–95. doi: ISSN: 0928-4931. Impact Factor: 5.080. Q1 6/33 Materials Science, Biomaterials. 

    9. J. Guillem-Marti, G. Boix-Lemonche, D. Gugutkov, M.P. Ginebra, G. Altankov, J.M. Manero. Recombinant fibronectin fragment III8-10/polylactic acid hybrid nanofibers enhance the bioactivity of titanium surface. Nanomedicine (Lond). 2018 Apr;13(8):899-912. Epub 2018 Mar 22. doi: 10.2217/nnm-2017-0342

    10. Y. Qi, Zh. Ye, Al. Fok, B.N. Holmes, M. Espanol, M.P. Ginebra, C. Aparicio. Effects of Molecular Weight and Concentration of Poly(Acrylic Acid) on Biomimetic Mineralization of Collagen. ACS Biomater. Sci. Eng., 2018, 4 (8), pp 2758–2766. DOI: 10.1021/acsbiomaterials.8b00512.

    11. M. Ortiz-Hernandez, K. S. Rappe, M. Molmeneu, C. Mas-Moruno, J. Guillem-Martí, M. Punset, C. Caparros, J. Calero, J. Franch, M. Fernandez-Fairen, J. Gil. Two Different Strategies to Enhance Osseointegration in Porous Titanium: Inorganic Thermo-Chemical Treatment Versus Organic Coating by Peptide Adsorption. Int. J. Mol. Sci. 2018, 19(9), 2574; doi:

    12. M. Hoyos-Nogués, J. Buxadera-Palomero, M.-P. Ginebra, J.M. Manero, F.X. Gil, C. Mas-Moruno. All-in-one trifunctional strategy: A cell adhesive, bacteriostatic and bactericidal coating for titanium implants. Colloids and Surfaces B: Biointerfaces 169 (2018) 30–40. doi: 10.1016/j.colsurfb.2018.04.050

    13. K. Khurana, F. Müller, K. Jacobs, Th. Faidt, J-U. Neurohr, S. Grandthyll, F. Mücklich, C. Canal, M.P. Ginebra. Plasma polymerized bioceramics for drug delivery: Do surface changes alter biological behaviour? European Polymer Journal 107 (2018) 25–33. doi:

    14. G. Scionti, L. Rodriguez-Arco, M.T. Lopez-Lopez, A.L. Medina-Castillo, I. Garzón, M. Alaminos, M. Toledano, R. Osorio. Effect of functionalized PHEMA micro- and nano-particles on the viscoelastic properties of fibrin-agarose biomaterials. J Biomed Mater Res A. 2018 Mar;106(3):738-745. doi: 10.1002/jbm.a.36275

    15. E. Vidal, J. Buxadera-Palomero, C. Pierre, J.M. Manero, M.P. Ginebra, S. Cazalbou, C. Combes, E. Rupérez, D. Rodriguez. Single-step pulsed electrodeposition of calcium phosphate coatings on titanium for drug delivery. Surface & Coatings Technology 358 (2019) 266–275. doi: 10.1016/j.surfcoat.2018.11.037.

    16. J.A. Picas, M. Punset, E. Rupérez de Gracia, S. Menargues, E. Martin, M.T. Baile Puig. Corrosion mechanism of HVOF thermal sprayed WC-CoCr coatings in acidic chloride media. Surface and coatings technology (2018). doi: . ISNN: 0257-8972. Impact Factor: 2.906. Q1 4/19 Materials Science, Coatings and Films

    17. C. Lo Porto, F. Palumbo, J. Buxadera-Palomero, C, Canal, P. Jelinek, L. Zajickova, P. Favia. On the plasma deposition of vancomycin-containing nano-capsules for drug-delivery applications. Plasma Process Polym. 2018;e1700232. doi:

    18. M. Hoyos-Nogués, F. J. Gil, C. Mas-Moruno. Antimicrobial Peptides: Powerful Biorecognition Elements to Detect Bacteria in Biosensing Technologies. Molecules 2018, 23, 1683; doi:10.3390/molecules23071683.

    19. A. Brizuela-Velasco, E. Pérez-Pevida, A. Jiménez-Garrudo, F.J. Gil-Mur, J.M. Manero, M. Punset-Fuste, D. Chávarri-Prado, M. Diéguez-Pereira6, F. Monticelli. Mechanical Characterisation and Biomechanical and Biological Behaviours of Ti-Zr Binary-Alloy Dental Implants. BioMed Research International, Volume 2017, Article ID 2785863, 10 pages. doi:

    20. M. Boutinguiza, M. Fernández-Arias, J. del Val, J. Buxadera-Palomero, D. Rodríguez, F. Lusquiños, F.J. Gil, J. Pou. Synthesis and deposition of silver nanoparticles on cp Ti by laser ablation in open air for antibacterial effect in dental implants. Materials Letters 231 (2018) 126–129. doi:

    21. F. Gil, E. Rupérez de Gracia, E. Velasco, C. Aparicio, J. M. Manero. Mechanism of fracture of NiTi superelastic endodontic rotary instruments. Journal of materials science. Materials in medicine. (2018) Volume 29 Issue 131. doi: ISSN: 0957-4530. Factor: 2.448. Q2 29/78 Engineering, Biomedical.

    22. L. Giner, M. Mercade, S. Torrent, M. Punset, R. Pérez-Antoñanzas, L. Delgado, F.J. Gil. Double acid etching treatment of dental implants for enhanced biological properties. J Appl Biomater Funct Mater. 2018 Apr;16(2):83-89. doi: 10.5301/jabfm.5000376. ISSN: 2280-8000. Impact Factor: 1.397. Q3 55/78 Engineering, Biomedical.

    23. J. Vilarrasa, L. Delgado, M. Galofré, J.M. Manero, In vitro evaluation of a multispecies oral biofilm over antibacterial coated titanium surfaces. J Mater Sci Mater Med. 2018 Nov 3;29(11):164. doi: 10.1007/s10856-018-6168-8. ISSN: 0957-4530. Factor: 2.448. Q2 29/78 Engineering, Biomedical.



    1. A. Barba, A. Diez-Escudero, Y. Maazouz, K. Rappe, M. Espanol, E.B. Montufar, M. Bonany, J.M. Sadowska, J: Guillem-Marti, C. Öhman-Mägi, C. Persson, M.C. Manzanares, J. Franch, M.P. Ginebra. Osteoinduction by Foamed and 3D-Printed Calcium Phosphate Scaffolds: Effect of Nanostructure and Pore Architecture. ACS Appl Mater Interfaces. 2017 Nov 20. doi: 10.1021/acsami.7b14175

    2. M. Hoyos-Nogués, F. Velasco, M.-P. Ginebra, J.M. Manero, F.X. Gil and C. Mas-Moruno. Regenerating bone via multifunctional coatings: the blending of cell integration and bacterial inhibition properties on the surface of biomaterials. ACS Appl Mater Interfaces. 2017 Jul 5;9(26):21618-21630. doi: 10.1021/acsami.7b03127.

    3. Y. Maazouz, E.B. Montufar, J. Malbert, M. Espanol, M.P.Ginebra. Self-hardening and thermoresponsive alpha tricalcium phosphate/pluronic pastes. Acta Biomaterialia 49 (2017) 563-574. doi:

    4. A. Diez-Escudero, M. Espanol, S. Beats, M.P. Ginebra. In vitro degradation of calcium phosphates: effect of multiscale porosity, textural properties and composition. Acta Biomaterialia 60 (2017):81-92. doi:

    5. R. O'Neill, H.O. McCarthy, E. Montufar, M.P. Ginebra, D.I. Wilson, A. Lennon, N. Dunne. Critical Review: Injectability of Calcium Phosphate Pastes and Cements. Acta Biomaterialia 50, 1 March 2017, Pages 1–19. doi:

    6. G. Ciapetti, G. di Pompo, A. Diez-Escudero, E.B. Montufar, M.P. Ginebra S. Avnet, D. Martini, N. Baldini. Osteoclast differentiation from human blood precursors on biomimetic calcium-phosphate substrates. Acta Biomaterialia 50, 1 March 2017, Pages 102–113. doi:

    7. C. Canal, R. Fontelo, I. Hamouda, J. Guillem-Martí, U. Cvelbar, M.P. Ginebra. Plasma-induced selectivity in bone cancer cells death. Free Radical Biology and Medicine 110 (2017) 72-80. doi:

    8. T.G. Kapp, F. Rechenmacher, S. Neubauer, O.V. Maltsev, E.A. Cavalcanti-Adam, R. Zarka, U. Reuning, J. Notni, H-J Wester, C. Mas-Moruno, J. Spatz, B. Geiger, H. Kessler. A Comprehensive Evaluation of the Activity and Selectivity Profile of Ligands for RGD-binding Integrins. Scientific Reports 7, Article number: 39805 (2017). doi:10.1038/srep39805

    9. R. Schieber, F. Lasserre, M. Hans, M. Fernández-Yagüe, M. Díaz-Ricart, G. Escolar, M.P. Ginebra, F. Mücklich, M. Pegueroles. Controlled endothelial cell and platelet adhesion onto patterned CoCr alloy surfaces by Direct Laser Interference Patterning technique for cardiovascular applications. Adv Healthc Mater. 2017 Jul 17. doi: 10.1002/adhm.201700327.

    10. A. Diez-Escudero, M. Espanol, X. Lu, C. Persson, M.-P. Ginebra. Heparinization of Beta Tricalcium Phosphate: Osteoimmunomodulatory Effects. Advanced Healthcare Materials, accepted November 2017.

    11. R. Fraioli, P.M. Tsimbouri, L.E. Fisher, A.H. Nobbs, B. Su, S. Neubauer, F. Rechenmacher, H. Kessler, M.P. Ginebra, M.J. Dalby, J.M. Manero, C Mas-Moruno. Towards the cell-instructive bactericidal substrate: exploring the combination of nanotopographical features and integrin selective synthetic ligands. Scientific Reports 7, Article number: 16363 (2017). doi:10.1038/s41598-017-16385-3.

    12. M. Motisuke, G. Mestres, C. O. Renó, R.G. Carrodeguas, C.A.C. Zavaglia, M.P. Ginebra. Influence of Si substitution on the reactivity of α-Tricalcium Phosphate. Materials Science and Engineering C, Volume 75, 1 June 2017, Pages 816-821. doi:

    13. J. Buxadera-Palomero, C. Calvo, S. Torrent-Camarero, F.J. Gil, C. Mas-Moruno, C. Canal, D. Rodríguez. Biofunctional polyethylene glycol coatings on titanium: An in vitro-based comparison of functionalization methods. Colloids Surf B Biointerfaces. 2017 Jan 24;152:367-375. doi: 10.1016/j.colsurfb.2017.01.042.

    14. A. Diez-Escudero, M. Espanol, E.B. Montufar, G. Di Pompo, G. Ciapetti, N. Baldini, M.P. Ginebra. Focus ion beam / Scanning electron microscopy characterisation of osteoclastic resorption of calcium phosphate substrates. Tissue Eng Part C Methods. 2017 Feb;23(2):118-124. doi: 10.1089/ten.TEC.2016.0361.

    15. J.M. Sadowska, J. Guillem-Marti, E.B. Montufar, M. Espanol, M.P. Ginebra. Biomimetic versus Sintered Calcium Phosphates: The in vitro Behavior of Osteoblasts and Mesenchymal Stem Cells. Tissue Eng Part A. 2017 Jan 20. doi: 10.1089/ten.TEA.2016.0406.

    16. A. Rodríguez-Contreras, Y. García, J.M. Manero, E. Rupérez. Antibacterial PHAs coating for titanium implants. European Polymer Journal. Volume 90, May 2017, Pages 66–78. doi:

    17. M.I. Castellanos, J. Guillem-Marti, C. Mas-Moruno, M. Díaz-Ricart, G. Escolar, M.P. Ginebra, F.J. Gil, M. Pegueroles, J.M. Manero. Cell adhesive peptides functionalized on CoCr alloy stimulate endothelialization and prevent thrombogenesis and restenosis. J Biomed Mater Res Part A 2017:00A:000–000. doi: 10.1002/jbm.a.35988.

    18. M.I. Castellanos, C. Mas-Moruno, A. Graua, X. Serra-Picamal, X. Trepat, F. Albericio, M. Joner, F.J. Gil, M.P. Ginebra, J.M. Manero, M. Pegueroles. Functionalization of CoCr surfaces with cell adhesive peptides to promote HUVECs adhesion and proliferation. Applied Surface Science 393 (2017) 82–92. doi:

    19. I. Ajaxon, A. Acciaioli, G. Lionello, M.P. Ginebra, C. Öhman-Mägi, M. Baleani, C. Persson. Elastic properties and strain-to-crack-initiation of calcium phosphate bone cements: revelations of a high-resolution measurement technique. J Mech Behav Biomed Mater. 2017 Oct;74:428-437. doi: 10.1016/j.jmbbm.2017.06.023.

    20. S. Gallinetti, G. Mestres, C. Canal, C. Persson, M.P. Ginebra. A novel strategy to enhance interfacial adhesion in fiber-reinforced calcium phosphate cement. Journal of Mechanical Behaviour of Biomedical Materials 75 (2017) :495-503. doi: 10.1016/j.jmbbm.2017.08.017.

    21. U. Cvelbar, C. Canal, M. Hori. Editorial: Plasma-inspired biomaterials. J. Phys. D: Appl. Phys. 50 (2017) 040201 (4pp) doi:10.1088/1361-6463/50/4/040201.

    22. E. Gilabert-Chirivella, R. Perez, C. Ribeiro, S. Ribeiro, D.M. Correia, M.L. Gonzalez-Martin, J.M. Manero, S. Lanceros-Mendez, G. Gallego, J. Gómez. Chitosan patterning on titanium implants. Progress in Organic Coatings. Volume 111, October 2017, Pages 23–28. doi:

    23. S. Lewin, A. Barba, C. Persson, J. Franch, M.P. Ginebra, C. Öhman-Mägi. Evaluation of bone formation in calcium phosphate scaffolds with μCT-method validation using SEM. Biomed. Mater. 12 (2017) 065005. doi:

    24. M. Herrero-Climent, M.M. Romero Ruiz, P. Lázaro Calvo, J.V. Ríos Santos, R.A. Perez, F.J Gil Mur. Effectiveness of a new dental implant bioactive surface: histological and histomorphometric comparative study in minipigs. Clin Oral Investig. 2017 Oct 12. doi: ISSN: 1432-6981. Impact Factor: 2.207. Q1 21/89 Dentistry, Oral Surgery & Medicine.

    25. E. Velasco, L Monsalve-Guil, A. Jimenez, I. Ortiz, J.Moreno-Muñoz, E. Nuñez-Marquez, M. Pegueroles, R A. Pérez, F.J. Gil. Importance of the Roughness and Residual Stresses of Dental Implants on Fatigue and Osseointegration Behavior. In Vivo Study in Rabbits. Journal of Oral Implantology, Vol. XLII /No. Six /2016. doi: 10.1563/aaid-joi-D-16-00088.

    26. P.Sevilla, J.Gil, C.Aparicio. Relevant Properties for Immobilizing Short Peptides on Biosurfaces. IRBM 38(2017)256–265. doi: ISSN: 1959-0318.  


    For full papers, please follow the link in FUTUR (UPC).